Biotechnology and Biopharmaceuticals: Transforming Proteins and Genes into Drugs defines biotechnology from the perspective of pharmaceuticals. The first section focuses on the process of transforming a biologic macromolecule into a therapeutic agent, while the second section provides a brief overview of each class of macromolecule with respect to physiological role and clinical application. Additional detail is also provided in the second section for each FDA approved, recombinantly derived biopharmaceutical for each category of macromolecule. The final section looks to the future and the new advances that will enhance our ability to develop new macromolecules into effective biopharmaceuticals. This last section discusses various drug delivery strategies while also describing gene and cell therapy strategies.
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Editorial Reviews
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“...a useful book for a...class in the pharmacology and pharmacokinetics of biotechnology-derived products, as well as a good introductory book for people new to the biotechnology industry.” (Pharmaceutical Research, Vol. 20, No. 12, December 2003)
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"...faculty that teach in the pharmaceutics curriculum will find the Ho and Gibaldi text of great value as course content is revised and new areas are added and expanded. The book provides important linkages between the science and therapeutics of biotechnology products that faculty will find useful in integrating the subject matter in health sciences and graduate program curricula." --Stuart Feldman, Ph.D., Biomedical and Health Sciences Institute and Department of Pharmaceutical and Biomedical Sciences, University of Georgia, Athens, Georgia
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5 of 5 people found the following review helpful:
3.0 out of 5 stars
Disappointingly written and edited,
By Carol D. Branca (Racine, WI United States) - See all my reviews
This review is from: Biotechnology and Biopharmaceuticals: Transforming Proteins and Genes into Drugs (Paperback)
This book appears to me to be very poorly edited, with numerous clerical and scientific errors. For instance, multiple sclerosis is termed a "neurogenerative" disease rather than a "neurodegenerative" disease. The writing includes some of the longest sentences I've ever seen in scientific writing, and not to the author's benefit. The authors repeat themselves quite a bit from one chapter to the next. Disappointing!
2 of 2 people found the following review helpful:
3.0 out of 5 stars
general introduction book for biological science,
By A Customer
This review is from: Biotechnology and Biopharmaceuticals: Transforming Proteins and Genes into Drugs (Paperback)
This book is only provided general information for biological science.The main part is focus on the drug information, which can be found in the public resources.Little information is mentioned about how to develop a new drug.Thus, it is suitable for undergranduate student reading, not for academic research.
5.0 out of 5 stars
Useful Book,
By A Customer
This review is from: Biotechnology and Biopharmaceuticals: Transforming Proteins and Genes into Drugs (Paperback)
"...faculty that teach in the pharmaceutics curriculum will find the Ho and Gibaldi text of great value as course content is revised and new areas are added and expanded. The book provides important linkages between the science and therapeutics of biotechnology products that faculty will find useful in integrating the subject matter in health sciences and graduate program curricula." --Stuart Feldman, Ph.D., Biomedical and Health Sciences Institute and Department of Pharmaceutical and Biomedical Sciences, University of Georgia, Athens, Georgia
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Inside This Book
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First Sentence:
Since the discovery in 1800 that the human body is composed of cells and proteins that are susceptible to but can also fight off pathogenic microbes, the perceived battlefield has challenged our imagination to develop biopharmaceuticals-biologically based therapeutic products. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
coagulation recombinant, cytokines human recombinant, derivatives globulin, lispro protamine suspension, formal drug interaction studies, radioimmune conjugate, human regular insulin, genetically engineered plasmid containing, human insulin injection, orphan drug regulations, follitropin alfa, regular human insulin, isophane suspension, recombinant host cells, compensated liver disease, monoclonal clone, follitropin beta, orphan drug designation, orphan product, antibody derivatives, ganirelix acetate, sterile lyophilized powder, pharmaceutical scale, orphan designation, drug delivery strategies Key Phrases - Capitalized Phrases (CAPs): (learn more)
Administration Dosage, United States, Proc Natl Acad Sci, New York, Pharm Res, John Wiley, Biol Chem, Cancer Res, Lupron Depot, Eli Lilly, Pharm Sci, Regranex Gel, Clin Oncol, Nat Med, Orphan Drug Act, Steering Committee, Biochim Biophys Acta, Hum Gene Ther, Anal Biochem, Amgen Inc, Ann Intern Med, European Union, Mol Biol, South San Francisco, Dev Biol Stand New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Since the discovery in 1800 that the human body is composed of cells and proteins that are susceptible to but can also fight off pathogenic microbes, the perceived battlefield has challenged our imagination to develop biopharmaceuticals-biologically based therapeutic products. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
coagulation recombinant, cytokines human recombinant, derivatives globulin, lispro protamine suspension, formal drug interaction studies, radioimmune conjugate, human regular insulin, genetically engineered plasmid containing, human insulin injection, orphan drug regulations, follitropin alfa, regular human insulin, isophane suspension, recombinant host cells, compensated liver disease, monoclonal clone, follitropin beta, orphan drug designation, orphan product, antibody derivatives, ganirelix acetate, sterile lyophilized powder, pharmaceutical scale, orphan designation, drug delivery strategies Key Phrases - Capitalized Phrases (CAPs): (learn more)
Administration Dosage, United States, Proc Natl Acad Sci, New York, Pharm Res, John Wiley, Biol Chem, Cancer Res, Lupron Depot, Eli Lilly, Pharm Sci, Regranex Gel, Clin Oncol, Nat Med, Orphan Drug Act, Steering Committee, Biochim Biophys Acta, Hum Gene Ther, Anal Biochem, Amgen Inc, Ann Intern Med, European Union, Mol Biol, South San Francisco, Dev Biol Stand New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 6
books:
See all 6 books this book cites
1
book
cites this book:
- Viral Hepatitis by Howard C. Thomas on page 184
- Clinical Oncology, 3e by Martin Abeloff on page 136
- Basic Biotechnology by Colin Ratledge on page 79
- Multiple Sclerosis by Donald W. Paty on page 187
- Cancer Medicine by James F. Holland on page 173
See all 6 books this book cites
- Math & Bio 2010: Linking Undergraduate Disciplines by Lynn Arthur Steen in Back Matter
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