Blood-Spinal Cord and Brain Barriers in Health and Disease [Hardcover]

Hari Shanker Sharma (Author)

Book Description

Publication Date: December 5, 2003 | ISBN-10: 0126390118 | ISBN-13: 978-0126390117 | Edition: 1

Recent research into the anatomy and pathophysiology of the blood-brain and blood-spinal cord barriers suggests that a breakdown in these barriers can result in several diseases affecting the central nervous system (CNS). This book presents new findings in the area of blood-brain barrier research that suggest barriers play important roles in health and disease conditions. It also discusses the development of new drugs that can modulate the barrier function in the CNS and may provide new approaches to treating neurological diseases such as Alzheimer's disease and other motor neuron diseases, as well as spinal cord trauma.

Key Features
* Presents the recent progress made in the research on the blood-brain and spinal cord barrier
* Contains numerous illustrations of light and electron micrographs
* Includes Foreword written by two eminent researchers in the field, Milton Brightman and Jorge Cervos-Navarro

Editorial Reviews

Review

"'Blood-Spinal Cord and Brain Barriers in Health and Disease' is a contemporary and very informative volume that should be a ready source of reference for all researchers and clinicians concerned with the CNS in health and disease."
--Cerebrospinal Fluid Research (June 2005)

Book Description

Discusses the role of the blood-brain and blood-spinal barriers in human health and disease.

See all Editorial Reviews

Product Details

• Hardcover: 605 pages
• Publisher: Academic Press; 1 edition (December 5, 2003)
• Language: English
• ISBN-10: 0126390118
• ISBN-13: 978-0126390117
• Product Dimensions: 11.1 x 8.5 x 1.3 inches
• Shipping Weight: 4.2 pounds
• Average Customer Review: 4.0 out of 5 stars  See all reviews (1 customer review)
• Amazon Best Sellers Rank: #2,499,935 in Books (See Top 100 in Books)

Customer Reviews

Most Helpful Customer Reviews

1 of 1 people found the following review helpful:

4.0 out of 5 stars Probably the best single book to date on the subject, October 12, 2004

By 

bbbPhD (USA) - See all my reviews

This review is from: Blood-Spinal Cord and Brain Barriers in Health and Disease (Hardcover)

FULL DISCLOSURE--I work closely with several of the contributing authors in this book.

This book has been an indispensible resource in the preparation of my doctoral dissertation, which is on the blood-brain barrier. I would heartily recommend it to anyone interested in the field at the graduate student level or higher. The treatment of some subjects is a little uneven, but that is to be expected in a book that covers so much ground--from molecular biology and biophysics of tight junction proteins to clinical aspects of the BBB--in a single volume. The illustrations are attractive and clear, and most of the chapters are very well-written.

Overall, an excellent reference for researchers in the BBB field, and a great introduction to many aspects of the field for scientists or clinicians wanting to know more about it.