Brain Tumor Immunotherapy [Hardcover]

Linda M. Liau (Editor), Donald P. Becker (Editor), Timothy F. Cloughesy (Editor), Darell D. Bigner (Editor)

Book Description

ISBN-10: 0896036383 | ISBN-13: 978-0896036383 | Publication Date: January 15, 2001 | Edition: 1st

An authoritative panel of researchers and clinicians critically reviews the entire field to provide a comprehensive guide to modern brain tumor immunotherapy and thereby enhance future research in this area. The contributors detail many of the key laboratory experiments and clinical protocols that are currently being investigated, integrate the available information from previous and ongoing research, and help define the current status of the field. Topics range from adoptive cellular and antibody-mediated immunotherapy of brain tumors to tumor vaccines and related strategies, and include many vanguard experimental strategies and immunological techniques for studying brain tumor immunotherapy. Cutting-edge and comprehensive, Brain Tumor Immunotherapy brings together all the important recent advances in our understanding of central nervous system tumor immunology and illustrates in powerful detail the many new applications now harnessing the immune response for brain tumor therapeutics.

Editorial Reviews

Review

"...this multiauthored book is sufficiently complete to support the notion that malignant brain tumors in situ are amenable to therapies designed to isolate, amplify, and focus aspects of the immune response with respect to these tumors...Part II, Introduction to Immunotherapy of Brain Tumors, contains two very good chapters that provide the rational bases for numerous immunotherapeutic approaches covered in the remaining 12 chapters. ...Part III, Adoptive Cellular Immunotherapy, covers the more important issue of cell-mediated immunotherapy from both active immunization and adoptive transfer of ex vivo-expanded effector lymphocytes....Part IV Antiboby-Mediated Immunotherapy, contains four concise reviews of some of the more interesting anti-body-based approaches in treating brain tumors....This text should be a very useful reference for investigators who are interested in any therapeutic modality that involves (or affects) the immune system of patients with intrinsic brain tumors."- Neuro-Oncology "Brain Tumor Immunotherapy is a unique text in its compilation of current knowledge and experimental events from an authoritative panel of researchers and clinicians who describe the ongoing trends in immunotherapy research as promising therapeutic tools for the treatment of brain tumors....The basic concepts necessary to understanding immunotherapeutic approaches to the treatment of brain tumors are superbly presented in Part II....A concise but excellent overview of the immune system as applied to the central nervous system, this chapter presents the issues that later chapters deal with, namely heterogeneity of tumors, "restricted" immunological privilege, antigen-presenting mechanisms, and cellular immunogenic responses of the central nervous system, as well as the potential risk of allergic encephalomyelitis induction." - Journal of Neurosurgery

From the Back Cover

It is now clear from basic research and clinical trials that immunotherapy for brain tumors is feasible, can evoke relevant biologic responses, and can yield important insights into human biology. In Brain Tumor Immunotherapy, an authoritative panel of researchers and clinicians critically reviews the entire field to provide a comprehensive guide to modern brain tumor immunotherapy and thereby enhance future research in this area. The contributors detail many of the key laboratory experiments and clinical protocols that are currently being investigated, integrate the available information from previous and ongoing research, and help define the current status of the field. Topics range from adoptive cellular and antibody-mediated immunotherapy of brain tumors to tumor vaccines and related strategies, and include many vanguard experimental strategies and immunological techniques for studying tumor immunotherapy. Introductory material brings the reader up-to-date on the biological principles of brain tumor immunotherapy, along with the neuropathology, molecular pathogenesis, epidemiology, and the relevant current therapies. Cutting-edge and comprehensive, Brain Tumor Immunotherapy brings together all the important recent advances in our understanding of central nervous system tumor immunology and illustrates in powerful detail the many new applications now harnessing the immune response for brain tumor therapeutics.

Product Details

• Hardcover: 373 pages
• Publisher: Humana Press; 1st edition (January 15, 2001)
• Language: English
• ISBN-10: 0896036383
• ISBN-13: 978-0896036383
• Product Dimensions: 9.4 x 9.4 x 6.4 inches
• Shipping Weight: 1.2 pounds (View shipping rates and policies)
• Average Customer Review: 1.0 out of 5 stars  See all reviews (1 customer review)
• Amazon Best Sellers Rank: #3,295,178 in Books (See Top 100 in Books)

Customer Reviews

Most Helpful Customer Reviews

1.0 out of 5 stars Excellent book, but outdated, November 20, 2010

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A. Musella "Musella Foundation - virtualtrial... (Hewlett, NY) - See all my reviews
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This review is from: Brain Tumor Immunotherapy (Paperback)

This is not a new edition - just a new format.. excellent book when it was written many years ago but the field changes so quickly, It isn't that useful now.