CholestOff lowers cholesterol naturally and may reduce the risk of heart disease. CholestOff provides the extra 1.8 grams of plant sterols and stanols daily that many Americans need to reach National Institute of Health's guidelines. The average reduction in LDL cholesterol in six clinical studies of 3 weeks or longer supporting Reducol, the active ingredient found in Nature Made CholestOff, was 3.7% to 24.4%. Even if you watch your diet and exercise regularly it may not be enough to lower your cholesterol to heart healthy levels. That's where Nature Made Cholestoff can help. CholestOff is an all natural drug free blend of plant sterols and stanols, called Reducol which has been clinically proven to block cholesterol absorption and reduce LDL cholesterol (bad cholesterol) in as few as 21 days. As a result, taken as directed, Cholest-Off will lower your cholesterol levels and help support your cardiovascular health.* Many factors such as diet, body weight, physical exercise and age can affect your cholesterol levels. That is why a diet low in saturated fat and regular exercise are recommended as part of a cholesterol management along with consulting your physician on a regular basis to have your cholesterol levels checked. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.