Calcium Signalling in the Nervous System [Paperback]

P. G. Kostyuk (Author), Prof Alexei Verkhratsky (Author)

Book Description

Publication Date: February 1996 | ISBN-10: 0471959413 | ISBN-13: 978-0471959410 | Edition: 1

Calcium ions play an important role in the function of excitable cells, from the triggering of impulses in nerve cells to the regulation of biochemical pathways and basic cellular functions of all cell types in the nervous system. Calcium signalling is the main coupling mechanism linking external stimuli, via the membrane, with intracellular processes. Calcium Signalling in the Nervous System provides an up-to-date account of the most fundamental aspects of calcium signal generation in the nervous system, including pathways for Ca²⁺ influx, buffering in the cytosol, involvement of intracellular calcium stores and Ca²⁺ extrusion. The book also gives an overview of the most important aspects of interaction of Ca²⁺ ions with other messenger systems, the functional meaning of Ca²⁺ ions, as well as the pharmaceutical tools used for their dissection and modulation. The role of calcium in a variety of neural cell types and implications in brain function are also discussed, including the control of gene expression, cell differentiation and programmed cell death.

Editorial Reviews

From the Publisher

Provides an up-to-date account of the most fundamental aspects of calcium signal generation in the nervous system including pathways for Ca2+ influx, buffering in the cytosol, involvement of intracellular calcium stores and Ca2+ extrusion. The book also gives an overview of the most important aspects of interaction of Ca2+ ions with other messenger systems, the functional meaning of Ca2+ ions, as well as the pharmaceutical tools used for their dissection and modulation. The role of calcium in a variety of neural cell types and implications in brain function are also discussed including the control of gene expression, cell differentiation and programmed cell death.

Product Details

• Paperback: 220 pages
• Publisher: John Wiley & Sons; 1 edition (February 1996)
• Language: English
• ISBN-10: 0471959413
• ISBN-13: 978-0471959410
• Product Dimensions: 9.8 x 6.9 x 0.8 inches
• Shipping Weight: 1.2 pounds
• Amazon Best Sellers Rank: #8,820,561 in Books (See Top 100 in Books)

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