Calming the Brain addresses the entire field of research on minor tranquilizers and its application to current clinical practice in the treatment of anxiety and insomnia. These drugs are principally the benzodiazepines and related drugs, such as zolpidem and zopiclone. The text describes the molecular mechanism of action of benzodiazepines. Recent advances have helped define the physiochemical nature of the interaction between such drugs and their receptor protein, and thus pave the way for the design of new drugs. Other topics include the use of these drugs as anesthetics; the advantages and limitations of their use for anxiety, insomnia and epilepsy; and issues of tolerance and dependence.
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First Sentence:
Although herbal medicines have been used throughout history for the treatment of what would now be considered anxiety disorders and insomnia, the advent of chemically derived drugs prescribed on the basis of a biological model of brain function and dysfunction can be identified as the introduction of bromides by Sir Charles Locock, president of the Royal Society of Medicine in 1865. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
receptor subunit isoforms, benzodiazepine full agonists, myorelaxant effects, fourth hydrophobic segments, full agonist benzodiazepines, benzodiazepine receptor occupancy, classical benzodiazepines, subunit containing receptors, efficacy spectrum, full inverse agonists, agonist direction, receptor sensitivity changes, multiple benzodiazepine receptors, vivo binding studies, inverse agonist activity, chronic benzodiazepine treatment, unpunished responding, receptor oligomer, partial inverse agonists, benzodiazepine receptor ligands, anxiolytic activity, dorsal root potential, benzodiazepine binding site, ion channel family, benzodiazepine recognition site Key Phrases - Capitalized Phrases (CAPs): (learn more)
Mol Pharmacol, Pharmacol Exp Ther, Proc Natl Acad Sci, Brain Res, Life Sci, Biol Chem, Pharmacol Biochem Behav, New York, Clin Pharmacol, Trends Pharmacol Sci, Neurosci Lett, Raven Press, Med Chem, Arch Pharmacol, Prado de Carvalho, Trends Neurosci, Neurosci Biobehav Rev, Clin Psychiat, Hoffmann-La Roche, Int Clin Psychopharmacol, Mot Pharmacol, Nucl Med, Pharinacol Exp Ther, Drug Dev Res, Royal College of Psychiatrists New!
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Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Although herbal medicines have been used throughout history for the treatment of what would now be considered anxiety disorders and insomnia, the advent of chemically derived drugs prescribed on the basis of a biological model of brain function and dysfunction can be identified as the introduction of bromides by Sir Charles Locock, president of the Royal Society of Medicine in 1865. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
receptor subunit isoforms, benzodiazepine full agonists, myorelaxant effects, fourth hydrophobic segments, full agonist benzodiazepines, benzodiazepine receptor occupancy, classical benzodiazepines, subunit containing receptors, efficacy spectrum, full inverse agonists, agonist direction, receptor sensitivity changes, multiple benzodiazepine receptors, vivo binding studies, inverse agonist activity, chronic benzodiazepine treatment, unpunished responding, receptor oligomer, partial inverse agonists, benzodiazepine receptor ligands, anxiolytic activity, dorsal root potential, benzodiazepine binding site, ion channel family, benzodiazepine recognition site Key Phrases - Capitalized Phrases (CAPs): (learn more)
Mol Pharmacol, Pharmacol Exp Ther, Proc Natl Acad Sci, Brain Res, Life Sci, Biol Chem, Pharmacol Biochem Behav, New York, Clin Pharmacol, Trends Pharmacol Sci, Neurosci Lett, Raven Press, Med Chem, Arch Pharmacol, Prado de Carvalho, Trends Neurosci, Neurosci Biobehav Rev, Clin Psychiat, Hoffmann-La Roche, Int Clin Psychopharmacol, Mot Pharmacol, Nucl Med, Pharinacol Exp Ther, Drug Dev Res, Royal College of Psychiatrists New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
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