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Cancer Cytogenetics: Methods and Protocols (Methods in Molecular Biology)
 
 
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Cancer Cytogenetics: Methods and Protocols (Methods in Molecular Biology) [Hardcover]

John Swansbury (Editor)

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Cancer Cytogenetics: Methods and Protocols (Methods in Molecular Biology) Cancer Cytogenetics: Methods and Protocols (Methods in Molecular Biology)
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Book Description

1588290808 978-1588290809 March 10, 2003 1
A collection of key cytogenetic and FISH techniques used by modern clinical laboratories in the genetic analysis of human malignancies. The book's practical advice and methods are suitable for use at every level of expertise, including fully established laboratories, but with a sympathetic bias towards anyone considering setting up a new cytogenetics service. Here the reader will find not only elementary tutorials on the fundamentals of human karyotypes and chromosome analysis, but also detailed discussions on how laboratories may optimally upgrade their repertoire of capabilities to include such newer complementary techniques as CGH, FISH, and M-FISH.

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Editorial Reviews

Review

"Eminently practical for every stage of diagnostic service, this book offers laboratories a user-friendly collection of standard and advanced techniques, carefully designed to improve diagnosis and clinical management of cancer patients." - Clinical Laboratory International

"...an immensely useful book for anyone working in the field of cytogenetics. The author has filled this volume with the sort of detail that enables ready translation of methods into practice and provides clear explanations of individual steps within procedures..." - Cancer Forum

From the Back Cover

Cytogenetic studies of malignancy have become an essential tool in the clinical management of cancer patients, but they are not uniformly utilized, even in well-developed countries. In Cancer Cytogenetics: Methods and Protocols, experienced cytogeneticists describe in step-by-step detail the key cytogenetic and FISH techniques used by modern clinical laboratories in the genetic analysis of human malignancies, as well as explain how best to interpret the results.
The book's practical advice and methods are suitable for use at every level of expertise, including fully established laboratories, but with a sympathetic bias toward anyone considering setting up a new cytogenetics service. Here the reader will find not only elementary tutorials on the fundamentals of human karyotypes and chromosome analysis, but also detailed discussions on how laboratories may optimally upgrade their repertoire of available capabilities to include such newer complementary techniques as CGH, FISH, and M-FISH. Each protocol contains many novel ideas and time-saving techniques, expert commentary, tricks of the trade, alternative approaches, and suggestions that will help yield the results that clinicians want.
Eminently practical for every stage of diagnostic service, Cancer Cytogenetics: Methods and Protocols offers hospital and other pathology laboratories a user-friendly collection of both standard and advanced techniques, all carefully designed to improve the diagnosis and clinical management of cancer patients today.

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Inside This Book (learn more)
First Sentence:
The vast majority of published cytogenetic studies of malignancy have been of leukemias and related hematologic disorders (see Fig. 1), even though these constitute only about 20% of all cancers. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
lymphoid disorders other, common secondary abnormality, overnight colcemid, conventional cytogenetic study, conventional cytogenetic studies, adding colcemid, high hyperdiploidy, cytogenetics service, chromosome quality, malignancy cytogenetics, myeloid disorders, cancer cytogenetics, complex clone, add colcemid, excess thymidine, subtelomeric probes, constitutional karyotype, malignant myeloma, conventional cytogenetics, recurrent abnormalities, sole abnormality, fresh fixative, unstimulated cultures, centromeric probes, chromosome paints
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Cancer Genet, John Swansbury, Humana Press Inc, Texas Red, Genes Chromosomes Cancer, The Myeloid Disorders, Boehringer Mannheim, Difficult Choices, Analysis of the Human G-Banded Karyotype, Solving Problems, Cancer Res, Cell Genet, Leukemia Lymphoma, Leukemia Res, New York, Adult T-cell, Vector Laboratories Ltd
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