First of all, I also have a
Fujitsu ScanSnap S1500 Instant PDF Sheet-Fed Scanner for PC, and I will be comparing this Canon with my experience with the Fujitsu.
Both scanners have a nice small footprint and can scan a variety of paper sizes (although not large), including business cards. Both scanners do a very fast job at scanning the documents (duplex, in one pass - woohoo!).
What does separate these scanners from each other is the software. The Fujitsu comes with its own snapscan software coupled with Adobe Acrobat (standard version). This allows for a pretty standard setup with a large range of compatibility and support. The Canon comes with a 3rd party suite of software from Nuance. The pdf pro software is good and also has a wide range of options, maybe even more than the Adobe software. However, the Fujitsu snapscan software is just more user friendly and seems much easier to use. I have an easier time getting documents into and organized with the SnapScan software than I did with Canon's software. Again not a severe difference, but a little easier for sure ....
Overall, both scanners are very, very capable, but the software really seems to be the defining difference. Either of these scanners can do a great job of digitizing your life, and do it with accurate OCR software at incredible speeds. Both scanners can handle roughly the same capacity and page sizes. I have not "raced" them both side by side, but both scan at incredible speeds and create great looking images.
Again, the main difference is the software that comes with it. Both are very capable, but the SnapScan just seems a little easier to use, with a little more polished integration.
Bottom line: if you can get both at the same price, I might go with the Fujitsu, but if you can get the Canon at 50 bucks or more off, go that route. Either way, you will have a very good scanner to help you digitize your life and toss your file cabinets. Not to mention the ease of sharing documents with others and being able to find documents with a simple text search. Once you have the experience of finding a document that you need that way - you will never want to go back. These scanners are simply awesome and the Canon delivers alongside the Fujitsu.
** One of the comments listed on this review pointed out a very good issue: Unlike the Fujitsu, (which has a scanner and software made separately for mac and pc) the Canon has software that can work with PC and MAC at the same time. So if you have a "mixed" environment, then the Canon may win on this fact. That is a huge bonus .... Thanks!