Rheumatoid arthritis (RA) is the most common and most severe form of inflammatory arthritis. The pathogenesis of RA has been the subject of intense research for several decades. The prevailing hypotheses have changed over the years, and have attempted to incorporate the most recent data. Although T cells represent an important component of the cells which infiltrate the joint synovium, their contribution at a late stage of the disease remains a matter of debate. The goal of this book is to outline the major arguments and data suggesting that T cells may, or may not, be central players in the pathogenesis of chronic RA. While each of the editors and authors has his/her own bias (as will be clear by reading the respective chapters), our hope is that the readers will enjoy a complete and balanced view of the critical questions and experiments. This is not just an intellectual exercise since the direction of future therapeutic interventions depends heavily on how one interprets the pathogenesis of RA and the contribution of T cells.
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First Sentence:
Rheumatoid arthritis (RA) is a chronic inflammatory disease that affects about 1% of the general population worldwide [1 ]. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
normal human cartilage, lining macrophages, arthritogenic peptides, synovial fluid cells, synovial lining cells, synovial compartment, rheumatoid arthritis synovium, repertoire formation, shared epitope, rheumatoid synovium, synovial fibroblasts, synovial cells, collagen arthritis, synovial tissue, gene usage, lyme arthritis, cell repertoire, rheumatoid synovitis, third hypervariable region, chronic inflammatory arthritis, oligoclonal expansions, refractory rheumatoid arthritis, repertoire studies, reactive arthritis, cytokine balance Key Phrases - Capitalized Phrases (CAPs): (learn more)
Arthritis Rheum, Clin Invest, Exp Med, Ann Rheum Dis, Fxp Med, Verlag Basel, Proc Natl Acad Sci, Immunol Today, Infect Immun, Rheumatol Int, Biol Chem, Cell Biol, Clin Exp Immunol, Nature Med, New York, Ann Intern Med, University Hospital, Arthritis Rheun, Arthritis Rheurn, Association of the B-cell, Cain Invest, Cell Immunol, Clin Fxp Immunol, Textbook of Rheumatology, Waal Malefyt New!
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Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Rheumatoid arthritis (RA) is a chronic inflammatory disease that affects about 1% of the general population worldwide [1 ]. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
normal human cartilage, lining macrophages, arthritogenic peptides, synovial fluid cells, synovial lining cells, synovial compartment, rheumatoid arthritis synovium, repertoire formation, shared epitope, rheumatoid synovium, synovial fibroblasts, synovial cells, collagen arthritis, synovial tissue, gene usage, lyme arthritis, cell repertoire, rheumatoid synovitis, third hypervariable region, chronic inflammatory arthritis, oligoclonal expansions, refractory rheumatoid arthritis, repertoire studies, reactive arthritis, cytokine balance Key Phrases - Capitalized Phrases (CAPs): (learn more)
Arthritis Rheum, Clin Invest, Exp Med, Ann Rheum Dis, Fxp Med, Verlag Basel, Proc Natl Acad Sci, Immunol Today, Infect Immun, Rheumatol Int, Biol Chem, Cell Biol, Clin Exp Immunol, Nature Med, New York, Ann Intern Med, University Hospital, Arthritis Rheun, Arthritis Rheurn, Association of the B-cell, Cain Invest, Cell Immunol, Clin Fxp Immunol, Textbook of Rheumatology, Waal Malefyt New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 9
books:
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- Rheumatoid Arthritis, 1e by Edward D. Harris Jr. MD on page 122, page 123, and page 141
- Textbook of Rheumatology by William N. Kelley on page 122, and page 123
- Systemic Vasculitis: The Biological Basis (Infectious Disease and Therapy) by E. Carwile Leroy on page 143
- A Visit to the United Kingdom by Rachael Bell on page 39
- Rheumatoid Arthritis by Gary Firestein on page 17
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