Centrosomes and Spindle Pole Bodies, Volume 67 (Methods in Cell Biology) [Hardcover]

Robert E. Palazzo (Editor), Trisha N. Davis (Editor)

Book Description

Publication Date: September 10, 2001 | ISBN-10: 0125441703 | ISBN-13: 978-0125441704 | Edition: 1

Containing a comprehensive collection of convenient and quantitative methods for studying centrosomes, spindle pole bodies and related organelles, this text is a valuable resource for researchers and others interested in studying the role of these organelles in cell replication. Chapters outlining the role of these organelles in other cell functions are also included, and a wide variety of experimental systems for analyzing these organelles are presented. Detailed protocols for experiments are contained in each chapter for researchers to perform in their own labs. This volume outlines key methodologies used to analyze centrosomes and spindle pole bodies, their replication, and reproduction in the clear, well-illustrated style of the Methods in Cell Biology series.

Editorial Reviews

From the Back Cover

Centrosomes and Spindle Pole Bodies contains a comprehensive collection of convenient and quantitative methods for studying these and related organelles in cells from yeast to man. Chapters outlining methods for study of the role of these organelles in other cell functions including organization of the cytoskeleton and spindle assembly are provided. Written by experts in the field, this volume provides detailed methods for the structural, biochemical, and genetic analysis of these organelles from a wide variety of experimental systems. Methods for high-resolution electron microscopy tomography, light microscopy, and fluorescence localization of proteins are also included. In addition, various approaches and strategies for the identification of organelle components and experimental strategies aimed at understanding the funciton of these molecules are described. Each chapter provides sufficient detail to allow investigators to conduct the experiments outlined in their own laboratiories. This volume should prove valuable for investigators interested in pursuing the role of centrosomes and spindle pole bodies, and related microtubule-organizing centers, in cell and developmental biology and cancer.

Volume 67 of METHODS IN CELL BIOLOGY Prepared under the auspices of the American Society for Cell Biology --This text refers to the Paperback edition.

About the Author

Robert E. Palazzo, University of Kansas, U.S.A.
Trisha N. Davis, University of Washington, U.S.A.

Product Details

• Hardcover: 375 pages
• Publisher: Academic Press; 1 edition (September 10, 2001)
• Language: English
• ISBN-10: 0125441703
• ISBN-13: 978-0125441704
• Product Dimensions: 9.2 x 7.5 x 0.9 inches
• Shipping Weight: 1.9 pounds
• Amazon Best Sellers Rank: #9,180,804 in Books (See Top 100 in Books)