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Chemistry and Medicines: An Introductory Text
 
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Chemistry and Medicines: An Introductory Text [Hardcover]

James R Hanson (Author), Robin Ganellin (Author)

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Book Description

August 17, 2006
Medicinal chemistry incorporates bio-organic chemistry, organic synthetic methods, physical organic chemistry and organic reaction mechanisms. These areas of chemistry are crucial to the design and synthesis of new drugs, both in academia and the pharmaceutical industry. Chemistry and Medicines: An Introductory Text provides a general introduction to this fascinating subject. The first chapters contain a brief historical introduction followed by a description of the chemical features involved in the adsorption, distribution, metabolism and excretion of a drug. The remaining chapters describe the chemistry underlying the design and synthesis of some of the key drugs used to combat some major diseases of the peripheral and central nervous system, infectious diseases and cancers. A glossary and suggestions for further reading complete this textbook. The book is aimed at those studying advanced undergraduate and postgraduate courses in medicinal chemistry.

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Illustrates the drug development process through the thoughts of medicinal or organic synthesis chemists, and is a must read for all biochemists in the drug development sector. Destined for undergraduate chemists and biochemists, the book also offers general consultancy for post graduate and professional drug development research scientists.....each chapter includes a brief, developmental history and synthesis of the most popular drugs. Development and discovery of antiseptics such as Dettol, penicillins, ß-lactam antibiotics and AZT is most interesting. Cancer chemotherapy and the use of monoclonal antibodies are well covered in this introductory text. Then the big medical challenge: parasitic infections.

About the Author

Professor Hanson is Emeritus Professor of Chemistry

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