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Chronic Fatigue Syndrome: A Biological Approach
 
 
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Chronic Fatigue Syndrome: A Biological Approach [Hardcover]

Patrick Englebienne (Editor), Kenny De Meirleir (Editor)
5.0 out of 5 stars  See all reviews (3 customer reviews)

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Book Description

February 27, 2002 0849310466 978-0849310461 1
Chronic Fatigue Syndrome (CFS) is a complex, debilitating disorder, yet few current scientific biomedical books are available on the subject. The nonspecific symptoms, lack of diagnostic tests, and uncertainty as to the cause or causes of CFS make the disease that much more baffling. Chronic Fatigue Syndrome: A Biological Approach represents a monumental step in the journey to a unified understanding of CFS and establishes a scientific basis for treatment.

The book provides a rare treatise on current state of the art with respect to the worldwide scientifically documented basis of CFS and acknowledges the many as yet undiscovered or undefined pathogenic mechanisms involved in the production of symptoms. The authors, reflecting their clinical and basic research backgrounds, outline future research imperatives and direct clinicians toward appropriate diagnostic and therapeutic strategies.

Because of the multifactorial aspects of the disease, the book addresses various fields of the biomedical sciences, such as protein biochemistry, virology, and pharmacology. Many recent, biological discoveries help us better understand the physiology of this disease and improve the specificity of its diagnosis by laboratory tests. This book summarizes these advances and discusses insights that support CFS as a distinct and specific physical disease. Overall, Chronic Fatigue Syndrome: A Biological Approach provides a firm foundation understanding of CFS, opening the way for better diagnosis and design of new therapies

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Product Details

  • Hardcover: 312 pages
  • Publisher: CRC Press; 1 edition (February 27, 2002)
  • Language: English
  • ISBN-10: 0849310466
  • ISBN-13: 978-0849310461
  • Product Dimensions: 9.1 x 6.7 x 0.9 inches
  • Shipping Weight: 1.4 pounds (View shipping rates and policies)
  • Average Customer Review: 5.0 out of 5 stars  See all reviews (3 customer reviews)
  • Amazon Best Sellers Rank: #2,170,664 in Books (See Top 100 in Books)

 

Customer Reviews

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9 of 10 people found the following review helpful:
5.0 out of 5 stars Might launch 1000 medical studies!, August 6, 2003
By A Customer
This review is from: Chronic Fatigue Syndrome: A Biological Approach (Hardcover)
I'm not an M.D., but a struggling and strapped patient. So it wasn't written for me at all. Yet what is here is like a gift to me and all the others burdened by this horrible disabling disease. There are many chapters, each giving detailed information on different hypotheses, with real experimental findings by serious scientists, and with suggestions as to their possible significance. It is a collection of evidences, in terms that researchers, not patients, can utilize. In it are seeds, questions, and puzzles for future investigations. That much I can understand quite well.

I imagine that every day, there are scientists and medical researchers deciding on their next experimental undertaking. This book is sure to pique the interest of some who, without it, might have considered Chronic Fatigue Syndrome a field of futility.

I'm very grateful to the authors and publishers of this book. I'm outraged at the person who gave it a 1/5 rating, unread!!! Do you not want as many copies of this to get out into the world as possible? Not to be read by us, the patients, but by the next generation of doctors, pharmacologists, and medical researchers. Those for whom we all hope, holding our breath.

This book is worth ten other CFS books, in advancing the field of knowledge. I think this is likely to be the original source of much future research and could lead to some long-overdue answers. March on!

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7 of 8 people found the following review helpful:
5.0 out of 5 stars Could launch medical studies that bring answers!, August 17, 2003
By A Customer
This review is from: Chronic Fatigue Syndrome: A Biological Approach (Hardcover)
This book is clearly not written for the patient, but for the scientist. Especially the skeptic. It is an intriguing compilation, with scientific evidences, of numerous paths for future study. It certainly answers the question "is there any evidence this illness even exists?" and provides grist for future exploration. I'm very grateful to the author. There's HOPE!
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3 of 3 people found the following review helpful:
5.0 out of 5 stars Finally, a Medical Textbook on Chronic Fatigue Syndrome, October 31, 2007
By 
R. Chmelar "Bardamu" (New York, NY United States) - See all my reviews
(REAL NAME)   
This review is from: Chronic Fatigue Syndrome: A Biological Approach (Hardcover)
Just reading the research citations in this book is both informative and should give hope to anyone with CFS--now known as myalgic encephalopathy(ME)/CFS. Although I haven't been able to work in decades, luckily a have a master's degree in an area of health science, which enabled me to learn the ways and means of interpreting medical information. While this text is clearly written for the medical profession, I think if you have any kind of background at the collegiate level in health science, ie, biology, physiology, anatomy, etc. you should be able to glean a lot of useful information from this book. I'm sure the price is prohibitive for most of those with ME/CFS on disability, but if there's any way you can get your hands on a copy, I wholeheartedly recommend it. If not that, at least recommend it to your doctor(s).
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Inside This Book (learn more)
First Sentence:
Interferons (IFNs) were discovered through studies of viral interference mechanisms and extensively studied for their remarkable capacity to confer large spectrum antiviral protection in mammalian cells. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
ankyrin fragment, protein kinase homology domain, hyperalgesia response, ankyrin domain, inducer caspases, low molecular weight variants, galantamine hydrobromide, chronic pain response, antiviral pathway, symptom groupings, potential biochemical marker, apoptotic induction, chronic fatigue syndrome, postviral fatigue syndrome, mycoplasmal infections, inhibitor correlates, lower molecular weight fragments, viral reactivation, fatigue syndrome patients, clinical case definition, interferon action, oligoadenylate synthetase, mediated hypotension, immune dysfunction syndrome, cleavage parallels
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Cell Biol, Biological Approach, Interferon Cytokine Res, New York, Nucleic Acids Res, Interferon Res, Growth Horm, Kenny De Meirleir, Allergy Clin, Cancer Res, John Wiley, Nature Immunol, Patrick Englebienne, Academic Press, Cell Sci, Interferon Cvtokine Res, Nature Med, Pascale De Becker, Santa Cruz, University of Sydney, Vincent Herst, Anne D'Haese, Arthritis Rheum, Bernard Lebleu, Boca Raton
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