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Chronic Myeloid Leukemia
 
 
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Chronic Myeloid Leukemia [Hardcover]

Jorge Cortes (Editor), Michael Deininger (Editor)

Price: $129.95 & this item ships for FREE with Super Saver Shipping. Details
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Book Description

December 13, 2006 0849379555 978-0849379550 1

Chronic Myeloid Leukemia (CML) remains a key model for the improved understanding of the pathophysiology of a malignancy at a molecular level and has been used by researchers to develop a variety of therapies and therapeutic assessment methods. This concise, readable guide assembles and synthesizes the latest developments and trends in the treatment of CML and provides an authoritative and convenient summary of the latest progress in imatinib trials, the molecular monitoring of CML responses, and the engineering of new therapies to overcome resistance and improve patient care.


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About the Author

JORGE CORTES is Deputy Chair, Department of Leukemia, and Professor of Medicine, University of Texas M.D. Anderson Cancer Center, Houston, Texas. A member of several medical societies, Dr. Cortes has served as a lecturer and the author/co-author of over 300 medical publications and abstracts and has greatly contributed to the search for effective treatments for leukemias. Dr. Cortes is the recipient of a variety of awards including the Merit Award (1995) from American Society of Clinical Oncology, the Upjohn Outstanding Research Award (1995) from M.D. Anderson Cancer Center, and was recently a Clinical Research Scholar for the Leukemia Lymphoma Society. Dr. Cortes is the recipient of the Faculty Scholar Award from M.D. Anderson (2003), and the Celgene Young Investigator Award (2005).

MICHAEL DEININGER is Scientific Director of the CML Basic Research Program and Assistant Professor, Center for Hematologic Malignancies, Oregon Health & Science University, Portland. Dr. Deininger is a member of the American Society of Hematology and the American Society of Clinical Oncology. He received the M.D. degree from the University of Wuerzburg, Germany, and the Ph.D. degree from Imperial College, London. He has published numerous research and scholarly articles in peer-reviewed journals, covering molecular and clinical aspects of CML, and serves as a peer reviewer for Blood, Nature Genetics, The Lancet, Cancer Research, and other professional journals. Dr. Deininger’s honors include scholarships from the German Scholarship Foundation and the American Society of Hematology.


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Inside This Book (learn more)
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
blast crisis cells, major molecular response, imatinib resistance, high dose imatinib, imatinib dose, malignant hematopoietic progenitors, imatinib mesylate therapy, imatinib treatment, interferon alfa plus cytarabine, diagnosed chronic myeloid leukemia, imatinib therapy, residual leukemia cells, complete cytogenetic response, kinase domain mutations, crisis progenitors, kinase domain mutants, imatinib mesylate treatment, complete hematologic response, chronic myeloid leukemia patients, positive metaphases, major cytogenetic response, chronic phase chronic myeloid leukemia, differentiation arrest, chronic phase patients, cytogenetic responses
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Cancer Res, Clin Oncol, Proc Natl Acad Sci, Biol Chem, Leuk Res, United States, Nat Med, National Cancer Institute, Mol Cell Biol, Nat Rev Cancer, Natl Cancer Inst, Acta Haematol, Biol Blood Marrow Transplant, Exp Hematol, Exp Med, Nat Genet, Semin Hematol
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