Classics in Total Synthesis II: More Targets, Strategies, Methods (Vol. 2) [Paperback]

K. C. Nicolaou (Author), S. A. Snyder (Author)

Book Description

ISBN-10: 3527306846 | ISBN-13: 978-3527306848 | Publication Date: December 8, 2003 | Edition: 1

Classics in Total Synthesis II is the long awaited sequel to Classics in Total Synthesis, a book that has made its mark as a superb tool for educating students and practitioners alike in the art of organic synthesis since its introduction in 1996. In this highly welcomed second volume, K.C. Nicolaou and Scott A. Snyder discuss in detail the most impressive accomplishments in natural product total synthesis during the 1990s and the first years of the 21^st century. While all of the features that made the first volume of Classics so popular and unique as a teaching tool have been maintained, in this new treatise the authors seek to present the latest techniques and advance in organic synthesis as they beautifully describe the works of some of the most renowned synthetic organic chemists of our time.

 
Key features include:

• Systematically develops domino reactions, cascade sequences, biomimetic strategies, and asymmetric catalysis through the chosen synthesis
• Discusses cutting edge synthetic technologies in terms of mechanism and scope
• Presents new reactions, such as olefin metathesis, in mini-review style
• Includes abundant references for further reading
• CD with useful teaching material for lecturers is included with hardback version (ISBN 3-527-30685-4)

Graduate students, educators, and researchers in the fields of synthetic and medicinal chemistry will wish to have a copy of this book in their collection as an indispensable companion that both augments and supplements the original Classics in Total Synthesis.

From the reviews:

"... a volume, (...) which any chemist with an interest in synthetic organic chemistry will wish to acquire." –JACS (on the previous volume)

"...this superb book (...) will be an essential purchase for many organic chemists." –Nature (on the previous volume)

"...Classics II is undoubtedly an excellent bargain that is highly recommended to everybody interested in advanced organic chemistry. One of my co-workers confessed that Classics I was the book on his bedside table while he prepared his thesis defense. Isn't that the highest distinction for a monograph? I have every reason to believe that Classics II will equally stand the selection process by students (and probably their supervisors too)." –Angewandte Chemie, 2004

"Well, there is a new pleasant read for the advanced student and even the experienced. It is the second volume to the established Classics in Total Synthesis and it continues the series extremely well." –ChemBioChem, 2004

"...the real innovation of this volume is the inclusion of alternative pathways to the same target molecule by other researchers. This enables the reader to appreciate that there are also other solutions to certain structural problems than those of the original synthesis. ... Let us hope that K. C. Nicolaou and his associates will present us with these future achievements in the same clear, informative and innovative format they have with the previous two volumes." –Applied Organometallic Chemistry

Editorial Reviews

Review

"…a welcome addition to the library of organic chemists, young or old." (Journal of Natural Products, February 2006)

From the Back Cover

Classics in Total Synthesis II is the long awaited sequel to Classics in Total Synthesis, a book that has made its mark as a superb tool for educating students and practitioners alike in the art of organic synthesis since its introduction in 1996. In this highly welcomed new volume, K.C. Nicolaou and Scott A. Snyder discuss in detail the most impressive accomplishments in natural product total synthesis during the 1990s and the first years of the 21^st century. While all of the features that made the first volume of Classics so popular and unique as a teaching tool have been maintained, in this new treatise the authors seek to present the latest techniques and advance in organic synthesis as they beautifully describe the works of some of the most renowned synthetic organic chemists of our time.

• domino reactions, cascade sequences, biomimetic strategies, and asymmetric catalysis are systematically developed through the chosen synthesis
• cutting edge synthetic technologies are discussed in terms of mechanism and scope
• new reactions, such as olefin metathesis, are presented in mini-review style
• abundant references are given for further reading

Graduate students, educators, and researchers in the fields of synthetic and medicinal chemistry will wish to have a copy of this book in their collection as an indispensable companion that both augments and supplements the original Classics in Total Synthesis. --This text refers to the Hardcover edition.

See all Editorial Reviews

Product Details

• Paperback: 658 pages
• Publisher: Wiley-VCH; 1 edition (December 8, 2003)
• Language: English
• ISBN-10: 3527306846
• ISBN-13: 978-3527306848
• Product Dimensions: 10 x 7.5 x 1.1 inches
• Shipping Weight: 3.2 pounds (View shipping rates and policies)
• Average Customer Review: 5.0 out of 5 stars  See all reviews (2 customer reviews)
• Amazon Best Sellers Rank: #328,591 in Books (See Top 100 in Books)

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Customer Reviews

Most Helpful Customer Reviews

3 of 3 people found the following review helpful:

5.0 out of 5 stars This book is great, but ask yourself what you want from it, November 12, 2010

By 

Raghu - See all my reviews

This review is from: Classics in Total Synthesis II: More Targets, Strategies, Methods (Vol. 2) (Paperback)

This book is awesome, without doubt! Almost every focused Organic Chemist, or a synthetic chemist would definitely know this book. It gives a detailed analysis of the synthesis of popular compounds in a beautiful way. So beautifully that its almost as if you were having a conversation with the guy who designed the sequence. Its really valuable that way. However, know what you want. If you don't want to do synthesis for like the rest of your life, this book will give you a lot, but has no point unless you need it.

Also, one musn't try "learning" out of this book, but rather UNDERSTAND the APPLICATION of transforms. It also teaches you HOW to think. When I say, "learning", I mean, you can't memorize sequences, or the structures, you can just appreciate how they did it, and gives you a wider view of how YOU could apply them too. Hope that helped.

0 of 5 people found the following review helpful:

5.0 out of 5 stars essential for all chemists, March 12, 2007

By 

Donna K. Montavon (Chicago, IL United States) - See all my reviews
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This review is from: Classics in Total Synthesis II: More Targets, Strategies, Methods (Vol. 2) (Paperback)

all organic chemist need this set of books, i dont even need to say this they already know