Majoradvances in the diagnosis and treatment of oral clefts have been made in the past 50 years, and recent genetics and epidemiological studies have led to new theories about the causes of cleft lip and palate. Addressing issues that are relevant to clinicians, researchers and family members, this book is a comprehensive, well-illustrated, and up-to-date account of the many facets of this common disorder. The authors describe the embryological and molecular mechanisms of cleft causation, present and illustrate the genetic and epidemiological methods used to identify risk factors for oral clefts, and describe treatments by the various professionals of the cleft team. A section is also devoted to the integration of research findings into public health practice, including ethical and financial considerations. The book draws together such diverse disciplines as craniofacial development, gene mapping, epidemiology, medicine, ethics, health economics, and health policy and management, and it will be an invaluable reference work.
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Book Description
Editorial Reviews
Review
"The editor has to be congratulated for his task to assemble 54 contributors. Their list reads almost as who's who in cleft lip and palate...A truely magnificent book on so many problems, difficulties and opportunities associated with oral clefts."--European Journal of Plastic Surgery
"Considering the complexity of this common congenital malformation, Wyszynski succeeds in providing a comprehensive guide to current understanding of cleft lip and palate...an invaluable resource."--Lancet
"This book has come at a time when the outlook of oral cleft genetics is changing. It is a valuable resource and a useful guide to the current state of complex trait genetics, particularly from the often underrepresented viewpoint of the clinical and molecular scientist."--Genetic Epidemiology
"a panoramic yet in-depth view of all there is to know about cleft lip and palate: genetic and environmental factors that predispose to clefting, diagnosis, treatment, and prevention. In summary, the breadth, depth, readability, and organization of this book combine to make it an excellent state-of-the-art resource for a wide variety of people interested in orofacial clefting."--American Journal of Medical Genetics
"Diego Wyszynski has done an admirable job of assembling a collection of reviews of various aspects of the etiology and treatment of oral clefts. Of particular value to clinicians and well-informed family members is the section on treatment. The treatment of patients with oral clefts, from birth to adulthood, requires a well-coordinated team effort. This section does a good job of conveying the global nature and specific details of this comprehensive care."--Am. J. Hum. Genetics
"Considering the complexity of this common congenital malformation, Wyszynski succeeds in providing a comprehensive guide to current understanding of cleft lip and palate...an invaluable resource."--Lancet
"This book has come at a time when the outlook of oral cleft genetics is changing. It is a valuable resource and a useful guide to the current state of complex trait genetics, particularly from the often underrepresented viewpoint of the clinical and molecular scientist."--Genetic Epidemiology
"a panoramic yet in-depth view of all there is to know about cleft lip and palate: genetic and environmental factors that predispose to clefting, diagnosis, treatment, and prevention. In summary, the breadth, depth, readability, and organization of this book combine to make it an excellent state-of-the-art resource for a wide variety of people interested in orofacial clefting."--American Journal of Medical Genetics
"Diego Wyszynski has done an admirable job of assembling a collection of reviews of various aspects of the etiology and treatment of oral clefts. Of particular value to clinicians and well-informed family members is the section on treatment. The treatment of patients with oral clefts, from birth to adulthood, requires a well-coordinated team effort. This section does a good job of conveying the global nature and specific details of this comprehensive care."--Am. J. Hum. Genetics
About the Author
Diego F. Wyszynski is at National Institute of Dental and Craniofacial Research.
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Most Helpful Customer Reviews
0 of 1 people found the following review helpful:
5.0 out of 5 stars
Great book on clefts,
By
This review is from: Cleft Lip and Palate: From Origin to Treatment (Hardcover)
I agree. This book is the bible of cleft lip and palate.
0 of 1 people found the following review helpful:
5.0 out of 5 stars
Finally a great book on clefts,
By A Customer
This review is from: Cleft Lip and Palate: From Origin to Treatment (Hardcover)
This is the best book about cleft lip and palate I have ever had. I highly recommend it for professionals and parents. It is very complete, clear, and the illustrations are phenomenal.
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Inside This Book
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First Sentence:
The primary palate is the keystone to the upper lip and anterior portion of the definitive palate. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
surgical probands, craniofacial care, nonsyndromic cleft lip, periconceptional care, unilateral incomplete cleft lip, cleft care, including oral clefts, noncleft controls, cleft severity, noncleft group, residual labial, retinoic acid receptor loci, surgical iatrogenesis, cramofacial development, incisal foramen, maxillary orthopedics, normal palatogenesis, lateral palatal shelves, presurgical orthopedics, transforming growth factor alpha locus, nonsyndromic oral clefts, unilateral complete cleft lip, based pharyngeal flap, negative intraoral pressure, sphincter pharyngoplasty Key Phrases - Capitalized Phrases (CAPs): (learn more)
Hum Genet, Plast Reconstr Surg, Med Genet, New York, United States, Plast Surg, Nat Genet, Craniofac Genet Dev Biol, Pierre Robin, Oral Maxillofac Surg, Oxford University Press, Silva Filho, Dis Child, Van Demark, Nonsyndromic Croen, Obstet Gynecol, Proc Natl Acad Sci, Ann Otol Rhinol Laryngol, Capelozza Filho, Genes Dev, Genet Epidemiol, Pediatr Otorhinolaryngol, Color Fig, New Zealand, British Caucasian New!
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Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
The primary palate is the keystone to the upper lip and anterior portion of the definitive palate. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
surgical probands, craniofacial care, nonsyndromic cleft lip, periconceptional care, unilateral incomplete cleft lip, cleft care, including oral clefts, noncleft controls, cleft severity, noncleft group, residual labial, retinoic acid receptor loci, surgical iatrogenesis, cramofacial development, incisal foramen, maxillary orthopedics, normal palatogenesis, lateral palatal shelves, presurgical orthopedics, transforming growth factor alpha locus, nonsyndromic oral clefts, unilateral complete cleft lip, based pharyngeal flap, negative intraoral pressure, sphincter pharyngoplasty Key Phrases - Capitalized Phrases (CAPs): (learn more)
Hum Genet, Plast Reconstr Surg, Med Genet, New York, United States, Plast Surg, Nat Genet, Craniofac Genet Dev Biol, Pierre Robin, Oral Maxillofac Surg, Oxford University Press, Silva Filho, Dis Child, Van Demark, Nonsyndromic Croen, Obstet Gynecol, Proc Natl Acad Sci, Ann Otol Rhinol Laryngol, Capelozza Filho, Genes Dev, Genet Epidemiol, Pediatr Otorhinolaryngol, Color Fig, New Zealand, British Caucasian New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 19
books:
See all 19 books this book cites
1
book
cites this book:
- Cleft Lip and Palate: Long-Term Results and Future Prospects : The Presurgical Period, Initial Surgery, and Speech, Surgery and Growth by Ag Huddart on page 68, and page 443
- Cleft Palate Speech Management: A Multidisciplinary Approach by Robert J. Shprintzen PhD on page 318, and page 352
- Syndromes of the Head and Neck (Oxford Monographs on Medical Genetics) by Robert J. Gorlin D.D.S M.S. D.Sc. on page 64, and page 97
- Early Treatment of Cleft Lip and Palate by M. Hotz on page 396
- Oral Biology at the Turn of the Century: Misconceptions, Truths, Challenges & Prospects, Congress, Interlaken, August 1998 (30th Anniversary of the European Research Group for Oral Biology by S. Shapiro on page 12
See all 19 books this book cites
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