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The Clostridia: Molecular Biology and Pathogenesis
 
 
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The Clostridia: Molecular Biology and Pathogenesis [Hardcover]

Julian I. Rood (Editor), Bruce A. McClane (Editor), J. Glenn Songer (Editor), Richard W. Titball (Editor)


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Book Description

0125950209 978-0125950206 May 27, 1997 1
The clostridia are a group of bacteria of considerable medical and economic importance and include species responsible for generating the most potent toxins known to humans.
The Clostridia: Molecular Biology and Pathogenesis is a unique work, comprising the most complete reference on the clostridia for over 20 years, bringing together the results from some of the most innovative and exciting research in the past decade. Using a principle-oriented rather than taxonomic approach, the results from molecular biology research are placed in the context of their clinical significance, and the disease process as a whole.
This state-of-the-art work is truly comprehensive, covering and integrating the diverse topics of genetics, physiology, pathogenesis and cell biology.
Written and edited by world-renowned authorities, material is presented to give the reader an up-to-date knowledge of the pathogenic species of this important genus. Background information is followed by details of the genetics, molecular biology, biochemistry and disease mechanisms. The structure, function and mode of action of toxins and other virulence determinants is clearly presented. As such, this work will prove essential for students, teachers, research microbiologists, infectious disease clinicians, toxin specialists, and all those working in medical or veterinary bacteriology, microbial genetics and the pharmaceutical industries.

Key Features
* Covers appropriate medical and veterinary topics
* Contains authoritative contributions by international experts
* Presents the current state of knowledge and areas for future research
* Truly comprehensive--covers topics from molecular biology and physiology

Editorial Reviews

Review

"...the authors have succeeded in providing a state-of-the-art reference work that describes the latest details of the genetics, molecular biology, biochemistry, and disease mechanisms of clostridia... the book is well organized, well written and edited by authorities renowned for their work with clostridia... I highly recommend this book to anyone seeking to understand the current views regarding the pathogenesis of clostridial Disease."
--ASM NEWS
"The editors have been successful in their attempts to solicit an outstanding group of contributing authors who have written comprehensive reviews on their respective topics. This book should be viewed as a timely and unique resource covering the wide breath of applied and basic research efforts directed against understanding the biology and molecular pathogenesis of clostridial infections."
--DOODY'S PUBLISHING REVIEWS
"It is an impressive publication, clearly presented, well-illustrated and shows the extent of detailed knowledge now available on the Clostridia... The book would be a very valuable addition to university libraries and to the shelves of those who have a focus or interest in the pathogenesis of infectious diseases."
--AUSTRALIAN VETERINARY JOURNAL

From the Back Cover

The clostridia are a group of bacteria of considerable medical and economic importance and include species responsible for generating the most potent toxins known to humans.
The Clostridia: Molecular Biology and Pathogenesis is a unique work, comprising the most complete reference on the clostridia for over 20 years, bringing together the results from some of the most innovative and exciting research in the past decade. Using a principle-oriented rather than taxonomic approach, the results from molecular biology research are placed in the context of their clinical significance, and the disease process as a whole.
This state-of-the-art work is truly comprehensive, covering and integrating the diverse topics of genetics, physiology, pathogenesis and cell biology.
Written and edited by world-renowned authorities, material is presented to give the reader an up-to-date knowledge of the pathogenic species of this important genus. Background information is followed by details of the genetics, molecular biology, biochemistry and disease mechanisms. The structure, function and mode of action of toxins and other virulence determinants is clearly presented. As such, this work will prove essential for students, teachers, research microbiologists, infectious disease clinicians, toxin specialists, and all those working in medical or veterinary bacteriology, microbial genetics and the pharmaceutical industries.

Product Details

  • Hardcover: 533 pages
  • Publisher: Academic Press; 1 edition (May 27, 1997)
  • Language: English
  • ISBN-10: 0125950209
  • ISBN-13: 978-0125950206
  • Product Dimensions: 9.9 x 6.9 x 1.2 inches
  • Shipping Weight: 2.8 pounds
  • Amazon Best Sellers Rank: #4,052,076 in Books (See Top 100 in Books)

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Inside This Book (learn more)
First Sentence:
The genus Clostridium, traditionally defined as containing Gram-positive, anaerobic rod-shaped and endospore-forming bacteria, constitutes a phylogenetically incoherent genus. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
molecule membrane permeability alterations, cpe expression, cpe gene, small molecule permeability changes, histotoxic clostridial infections, catp gene, clostridial sialidases, comparison with other clostridial neurotoxins, extracellular toxin production, cpe promoter, epsilon prototoxin, native enterotoxin, clostridial phospholipases, perfringens epsilon toxin, plc promoter, perfringens enterotoxin gene, lam gene, enterotoxigenic isolates, gene detection assays, large complex formation, perfringens cells, plc gene, quail disease, small molecule permeability alterations, progenitor toxin
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Infect Immun, Biol Chem, Academic Press, New York, Clin Microbiol, Microbiol Lett, Inf Dis, Papua New Guinea, Appl Environ Microbiol, Mot Microbiol, Microbiol Rev, Vet Res, Vet Med, Cell Biol, Proc Natl Acad Sci, Antimicrob Agents Chemother, Biochem Biophys Res Commun, United States, Med Microbiol, Microbiol Immunol, Vet Rec, Aust Vet, Biochim Biophys Acta, Nucl Acids Res, Avian Dis
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