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Cocaine Abuse: Behavior, Pharmacology, and Clinical Applications
 
 
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Cocaine Abuse: Behavior, Pharmacology, and Clinical Applications [Hardcover]

Stephen T. Higgins (Editor), Jonathan L. Katz (Editor)

Price: $147.00 & this item ships for FREE with Super Saver Shipping. Details
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Book Description

September 15, 1998 0123473608 978-0123473608 1
Cocaine abuse remains a major public health problem and contributes to many of our most disturbing social problems, including the spread of infectious disease, crime, violence, and neonatal drug exposure. Cocaine abuse results from a complex interplay of behavioral, pharmacological, and neurobiological determinants. While a complete understanding of cocaine abuse is currently beyond us, significant progress has been made in preclinical research on fundamental determinants of this disorder. These advances are critically reviewed in the first section of this volume. Important advances also have been made in characterizing the clinical pharmacology of cocaine, and those advances have been extended to understanding individual vulnerability to cocaine abuse, development of effective treatments, and discussions of policy. Those advances are critically reviewed in the third section of this volume. Contributors to the book were selected because of their status as internationally recognized leaders in their respective areas of scientific expertise. Moreover, each is a proponent of the importance of a rigorous, interdisciplinary scientific approach to effectively addressing the problem of cocaine abuse. As such, this volume offers a coherent, empirically-based conceptual framework for addressing cocaine abuse that has continuity from the basic research laboratory through the clinical and policy arenas. Each of the specific chapters is sufficiently detailed, in-depth and current to be valuable to informed readers with specific interests while also offering a comprehensive overview for those who might be less informed or have broader interests in cocaine abuse. This blend of critical review within each chapter with an explicitly conceptual continuity that spans all of the chapters makes this volume a unique contribution to cocaine abuse in particular and substance abuse in general.

Key Features
* Discusses cocaine abuse within the context of current principles of psychology, pharmacology, neuroscience, genetics and epidemiology
* Chapters are all authored by scientific experts
* First of its kind book on cocaine abuse to recognize behavioral/environmental determinants
* Coverage is comprehensive
* Informative for experts and generalists alike

Editorial Reviews

Review

"Each of the 17 chapters elegantly weaves empirical research into discussions of the most plausible theories on topics that cover a wide array of questions... refreshingly, a great deal of conflicting literature and science is introduced, leaving the answers to future scientists and researchers to ponder and to investigate. Perhaps the most exciting aspect of this book is the way in which the data are presented. The assembled authors lead the reader through the basic and clinical research, cite the outcomes of the experiments already conducted, and finally, point to future areas of research that seem most likely to provide important discoveries... Texts like this one are an invaluable addition to a researcher's library..."
--CONTEMPORARY PSYCHOLOGY

From the Back Cover

Cocaine abuse remains a major public health problem and contributes to many of our most disturbing social problems, including the spread of infectious disease, crime, violence, and neonatal drug exposure. provides a comprehensive review of the complex interplay of behavioral, pharmacological, and neurobiological factors and explains the significant progress in preclinical research on fundamental determinants of this disorder.
Important advances also have been made in characterizing the clinical pharmacology of cocaine, and those advances have been extended to understanding individual vulnerability to cocaine abuse, developing effective treatments, and discussing policy. Cocaine Abuse offers a coherent, empirically based conceptual framework for addressing cocaine abuse that has continuity from the basic research laboratory through the clinical and policy arenas.
Each of the specific chapters is sufficiently detailed, in-depth and current to be valuable to informed readers with either specific or broad interests in cocaine abuse. This blend of critical review within each chapter with an explicitly conceptual continuity that spans all of the chapters makes this volume a unique contribution to cocaine abuse in particular and substance abuse research in general.

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Inside This Book (learn more)
First Sentence:
Because of the widespread abuse of cocaine, there has been a considerable amount of research on its pharmacological actions, its behavioral effects, and the adaptations that occur in response to its chronic usage. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
reinforcing stimulus effects, primary cocaine abusers, mesoaccumbens dopaminergic pathway, interoceptive effects, cocaine legalization, human cocaine abusers, continuous cocaine abstinence, intravenous cocaine injections, dopamine autoreceptor antagonist, discriminative stimulus effects, subiculum lesions, desipramine maintenance, treating cocaine abuse, combining cocaine, alternative nondrug reinforcers, ofdrug dependence, locomotor stimulant effects, psychomotor stimulant effects, cocaine challenges, amphetamine infusions, cocaine reinforcement, caine use, other behavioral effects, cocaine infusions, cocaine interactions
Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, American Journal, Experimental Therapeutics, Brain Research, National Institute, Research Monograph, Government Printing Office, United States, Archives of General Psychiatry, Life Sciences, Raven Press, Journal of Neuroscience, Journal of the American Medical Association, Van Dyke, Academic Press All, Elsevier Science, New England Journal of Medicine, American Psychiatric Association, European Journal of Pharmacology, Pharmacology Biochemistry, Journal of Pediatrics, Plenum Press, Clinical Psychology, Journal of Psychoactive Drugs, Journal of Substance Abuse Treatment
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