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Combinatorial Chemistry: A Practical Approach (Methods and Principles in Medicinal Chemistry)
 
 
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Combinatorial Chemistry: A Practical Approach (Methods and Principles in Medicinal Chemistry) [Hardcover]

Willi Bannwarth (Editor), Eduard Felder (Editor), Raimund Mannhold (Series Editor), Hugo Kubinyi (Series Editor), Hendrik Timmerman (Series Editor)


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Combinatorial Chemistry: From Theory to Application (Methods and Principles in Medicinal Chemistry) Combinatorial Chemistry: From Theory to Application (Methods and Principles in Medicinal Chemistry)
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Book Description

September 13, 2000 3527301860 978-3527301867 1
As we enter the new millennium, combinatorial chemistry is providing significant impetus to new innovations in synthetic chemistry. Combinatorial chemistry has rapidly become the rising star among research methods, allowing scientists to efficiently test the feasibility of a multitude of new compounds.
The pursuit of new drugs is but one challenging field in which these combinatorial methods are particularly advantageous, helping researchers meet the modern-day demands of a highly competitive environment.
This book emphasises that modern combinatorial synthesis is possible not only in the solid phase, but also in solutions. Moreover, it discusses computer-assisted methods as well as the apparatus and instrumentation required for the combinatorial method. Successful and experienced researchers in the leading pharmaceutical companies and most renowned research institutes offer a solid insight and perspective into this diverse field.
A 'must' for every scientist in the area of pharmaceutical research

Editorial Reviews

Review

"...this book is recommended to newcomers in the field of combinatorial chemical synthesis because of its broad scope." (Journal of the American Chemical Society, Vol. 123, No. 35)

Product Details

  • Hardcover: 450 pages
  • Publisher: Wiley-VCH; 1 edition (September 13, 2000)
  • Language: English
  • ISBN-10: 3527301860
  • ISBN-13: 978-3527301867
  • Product Dimensions: 9.5 x 7 x 1.2 inches
  • Shipping Weight: 2.2 pounds
  • Amazon Best Sellers Rank: #6,618,923 in Books (See Top 100 in Books)

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Inside This Book (learn more)
First Sentence:
Within the pharmaceutical industry, one of the major aims is to increase the number of new chemical entities (NCEs) launched each year. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
levoglucosan derivative, alkene residues, reactive gas chemistry, tilted centrifugation, cyclative cleavage, pharmacophore centers, substructure descriptors, tryptophane derivative, autocorrelation descriptors, sample swings, solid phase version, amide library, aryl stannane, cleavage from the support, solid phase organic chemistry, traceless linker, resin bearing, linker unit, orbital shaking, chemical space, tetramic acids, resin capture, benzophenone imine, multicomponent reactions, linkers based
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Tetrahedron Lett, Perkin Trans, Agitation Temperature, Mettler Toledo Myriad, New York, Van de Waterbeemd, Cross-Linked Polystyrene Support, Drug Discovery Today, Comb Chemistry, Comprehensive Organic Synthesis, Computer-Assistent Library Design, Rapp Polymere, Argonaut Quest, Argonaut Technologies, Conditions Electrophile Reference, Entry Structure, Pure Appl, Robbins Scientific
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