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Combinatorial Chemistry: Synthesis, Analysis, Screening [Hardcover]

Günther Jung (Editor)


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Book Description

352729869X 978-3527298693 April 14, 2000 1
The story of success goes on and on - with a new book on combinatorial chemistry, edited by Günther Jung!

Combinatorial chemistry is a proven time- and resource-saving synthetic method of outstanding importance for industrial processes. Compound libraries help to save time and money, especially in the search for new drugs, and therefore play a pivotal role in solving the problem of the worldwide increasing demand for new and more active drugs. Not only substances, which are of interest for pharmaceutical chemistry, but also materials, catalysts, and biomolecules such as DNA or oligosaccharides are readily available with high structural diversities. The broad scope of combinatorial sciences is reflected by this book, edited by Günther Jung: The synthetic methods discussed range from solid-phase to solution-phase synthesis, from preparations of small molecules such as amines or alcohols to those of complex biomolecules. Feasible methods, efficient techniques, new trends in automation, and state-of-the-art fast instrumental analytical and screening methods are presented with many practical tips and tricks for everybody working in combinatorial chemistry.

This is the book written by specialists for specialists and for everyone aspiring to become an insider! It is an indispensible source of information for researchers working in organic synthesis, catalysis, biochemistry, and biotechnology, pharmaceutical and clinical chemistry, material sciences, and analytical chemistry.

Editorial Reviews

Review

"...this book discusses solid-phase and solution-phase synthesis, preparations of small molecules, and preparations of complex biomolecules." (SciTech Book News, Vol. 25, No. 4, December 2001)

Product Details

  • Hardcover: 634 pages
  • Publisher: Wiley-VCH; 1 edition (April 14, 2000)
  • Language: English
  • ISBN-10: 352729869X
  • ISBN-13: 978-3527298693
  • Product Dimensions: 9.5 x 7 x 1.5 inches
  • Shipping Weight: 3 pounds
  • Amazon Best Sellers Rank: #5,056,540 in Books (See Top 100 in Books)

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Inside This Book (learn more)
First Sentence:
Molecular medicine has changed the way that new drugs are discovered and optimized. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
core structure libraries, similarity radius, separate single compounds, glycopeptide libraries, automated combinatorial chemistry, glycopeptide library, oligosaccharide libraries, anchors cleaved, affinity fingerprints, polyamine resin, substructure keys, nonpeptide libraries, single resin beads, amide library, biosynthetic gene cluster, analyzer cell, multicomponent reactions, combinatorial synthesis, ion packages, parallel synthesis, different core structures, bead analysis, steric fields, loading domains, synthetic epitopes
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Tetrahedron Lett, New York, Protein Res, Liebigs Ann, Mass Spectrom, Rapid Commun, Perkin Trans, Academic Press, Ahlberg Randall, Nucleic Acids Res, San Diego, Exp Med, Angew Chem, Peptides Chemistry, Reaction Extracted, Verlag Chemie, Biol Chem, Boehringer Ingelheim, Doctoral Thesis, John Wiley, Nature Biotechnology, Plenum Press, Proc Natl Acad Sci, Reynolds Cody, Anal Biochem
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