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Combinatorial Peptide and Nonpeptide Libraries: A Handbook
 
 
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Combinatorial Peptide and Nonpeptide Libraries: A Handbook [Hardcover]

G?nther Jung (Editor)

Price: $200.00 & this item ships for FREE with Super Saver Shipping. Details
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Book Description

May 1997
With combinatorial chemistry millions of organic compounds can be produced simultaneously, quickly, and in most cases by automated procedures. These compound libraries are a cost-effective resource for the pharmaceutical industry in their search for biologically active lead structures. Furthermore simultaneous parallel synthesis of single peptides and peptide libraries solve the problem of the worldwide increasing demand for peptides. The synthetic methods described here in detail contribute to a forward-looking technology that has a high impact for industrial and academic research.

Fast and efficient analytical techniques are essential for using the complicated product mixtures and detecting by-products. Various synthetic approaches and technologies, mass spectrometry, and screening assays are discussed extensively.

This book is a must and an indispensible source of information for every researcher in this rapidly developing field, which spans organic synthesis, biochemistry, biotechnology, pharmaceutical, medicinal, and clinical chemistry.

Editorial Reviews

From the Publisher

The use of binatorial chemistry and peptide libraries in drug screening and development is a new and rapidly expanding technology. This first handbook on the topic contains background information and step-by-step experimental procedures. It will be indispensable for anyone working in the field.

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Inside This Book (learn more)
First Sentence:
The apparently unlimited microbial sources of novel natural products provide lead structures of highest molecular diversity and complexity. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
natural peptide libraries, most active peptide mixtures, stylostatin analogs, cyclic peptide libraries, calculated mass distribution, cyclopeptide libraries, different peptide mixtures, max mob, occurrence library, multiple sequence analysis, cyclopeptide library, most active amino acids, simultaneous multiple peptide synthesis, isobaric peptides, octapeptide libraries, premix methods, equimolar distribution, anchor amino acids, positive beads, benzodiazepine synthesis, permethylated compounds, oligomer libraries, simultaneous multiple synthesis, peptoid libraries, partial libraries
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Tetrahedron Lett, Peptide Symposium, Protein Res, Supplier Mesh, New York, Escom Verlag, Rapp Polymere, The Netherlands, Academic Press, Liebigs Ann, Angew Chem, Chiron Mimotopes, Collected Papers, Mayflower Worldwide Limited, Methods Enzymol, Peptides Int, Life Sci, Third International Symposium, Acids Res, Mayflower Worldwide Ltd, Applied Biosystems, Brominated Wang, Combinatorial Synthesis Symposium, Exploiting Molecular Diversity, Information Systems
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