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Comprehensive Natural Products Chemistry : Amino-acids, Peptides, Porphyrins and Alkaloids
 
 
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Comprehensive Natural Products Chemistry : Amino-acids, Peptides, Porphyrins and Alkaloids [Hardcover]

D.H.R. Barton (Author), O. Meth-Cohn (Author), J.W. Kelly (Author)

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Book Description

0080431569 978-0080431567 February 1, 1999
Hardbound. This volume covers the exciting advances made in the chemistry, biochemistry and molecular biology of amino acid, peptide and alkaloid biosynthesis. The fourteen chapters in this volume briefly introduce classical approaches to deciphering biosynthetic pathways, but largely focus on a synergistic approach, i.e. one applying both chemical and genetic methods to uncover the mysteries associated with the synthesis of some of the worlds most beautiful molecules. Two chapters review our current understanding of alkaloid biosynthesis, which provided much of the impetus for the growth of organic chemistry in the century. Two chapters are devoted to the biosynthesis of Heme prosthetic groups, which have attracted the attention of numerous chemists and biologists over the years. Five chapters focus on peptide and antibiotic biosynthesis, in keeping with the fantastic advances that have been made in understanding non-ribosomal peptide synthesis and the u

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Inside This Book (learn more)
First Sentence:
The biosynthesis of the aromatic amino acids tryptophan (Trp), tyrosine (Tyr), and phenylalanine (Phe) is almost twice as costly in terms of ATP than the synthesis of the remaining -amino acids, requiring 78, 62, and 65 mol of ATP, respectively, to synthesize 1 mol of these residues. Read the first page
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Academic Press, New York, San Diego, Harvard University, Oxford University, World War, Boca Raton, Controlled Steps, Cornell University, Ness York, Stanford University, Tokyo University, Cambridge University, Duilio Arigoni, Enzymatic Synthesis of Penicillins Using, Jerrold Meinwald, Marcel Dekker, Tohoku University
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