This long-awaited, greatly-expanded new edition of a best-selling guide offers an encyclopedic and systematic collection of useful synthetic methodology, including tens of thousands of reactions and synthetic transformations. The first edition has been reviewed in the professional journals as "clearly...the first choice for researchers seeking information on synthetic transformations." And as "useful to anyone who must do organic synthesis, especially those whose focus is not strictly organic chemistry. It provides a...clear road map to the synthetic literature and should be kept within easy reach of the chemist's desk."
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Book Description
Editorial Reviews
Review
". . . makes available at one's fingertips a wealth of information concerning a broad range of reaction types." -- Angewandte Chemie
"...an indispensable reference work for designing and carrying out modern organic chemical synthesis..." -- Analytical Biochemistry, Vol. 294, 2001
"...an outstanding work of reference...and will be an essential purchase for all synthetic organic chemists in academe and industry." -- Natural Products Reports, Vol 17, 2000
"...makes available at one's fingertips a wealth of information concerning a broad range of reaction types." -- Angewandte Chemie
"This edition covers 39 new journals and numerous additional reviews and books from 1988-95." -- SciTech Book News, March 2001
"This impressive work provides a comprehensive, highly condensed, systematic collection of useful synthetic methods for use if beginning students and experienced organic synthesis workers." -- SciTech Book News
From reviews of the first edition book...". . . first choice for researchers seeking information on synthetic transformations..." -- Journal of Natural Products
"...an indispensable reference work for designing and carrying out modern organic chemical synthesis..." -- Analytical Biochemistry, Vol. 294, 2001
"...an outstanding work of reference...and will be an essential purchase for all synthetic organic chemists in academe and industry." -- Natural Products Reports, Vol 17, 2000
"...makes available at one's fingertips a wealth of information concerning a broad range of reaction types." -- Angewandte Chemie
"This edition covers 39 new journals and numerous additional reviews and books from 1988-95." -- SciTech Book News, March 2001
"This impressive work provides a comprehensive, highly condensed, systematic collection of useful synthetic methods for use if beginning students and experienced organic synthesis workers." -- SciTech Book News
From reviews of the first edition book...". . . first choice for researchers seeking information on synthetic transformations..." -- Journal of Natural Products
From the Publisher
In Comprehensive Organic Transformations on CD-ROM: A Guide to Functional Group Preparations transformations are organized into major sections according to the class of functional group synthesized. Transformations within each section are grouped according to reaction type. Extensive tables list the most important reagents used to effect each transformation. All transformations presented are fully referenced, with citations from over 160 journals, books, and reviews. The Transformation Index lists all organic transformations covered in the text by chemical name, sorted in two ways: according to the organic product of the transformation (as in the print edition), and according to the organic starting material (a new feature).
--This text refers to the
CD-ROM
edition.
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Most Helpful Customer Reviews
36 of 38 people found the following review helpful:
4.0 out of 5 stars
Ignore the non-chemists reviewing this book.,
By Michael Koehler (Burlingame, CA USA) - See all my reviews
This review is from: Comprehensive Organic Transformations: A Guide to Functional Group Preparations (Hardcover)
I want to help others sort through the conflicting reviews of this book. As a PhD chemist, I can say unequivocally that this book is not for the non-professional, as I suspect the negative reviewers are. The indexing system is not intuitive, but makes sense once you've begun to use it. One of the reviewers complains that database searching is better than this book. This book is intended to help you find straightforward procedures for relatively straightforward reactions and allows you to look at the many things that have been tried to effect a given transformation. These are things that the databases can't help much with since these reactions have been done in the literature thousands of times, and any search will generate a huge mess of matches.
12 of 14 people found the following review helpful:
4.0 out of 5 stars
Not excellent, but very good,
By gregory.schaaf@wright.edu (Dayton, OH, USA) - See all my reviews
This review is from: Comprehensive Organic Transformations: A Guide to Functional Group Preparations (Hardcover)
This is a very good book for looking up references on a great variety of transformations. This book is probably not as good a March's book, but complements it very well. Between these two books, you can probably find any reference you want.
2 of 2 people found the following review helpful:
5.0 out of 5 stars
A must have for any medicinal chemist,
By
This review is from: Comprehensive Organic Transformations: A Guide to Functional Group Preparations (Hardcover)
This is one of the best reference books to use if something in literature doesn't go according to plan...which it almost always does.
It's also extremely helpful in drug design and helping plan those unknown reactions, etc. I don't think this would be helpful to anyone except organic or synthetic chemists.
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Inside This Book
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Key Phrases - Statistically Improbable Phrases (SIPs):
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forms silyl ether, cat bis, ketone diastereoselectivity, cat hydroquinone, serial cyclization, double bond transposition, cat chiral, chiral lactam, enol silane, cat vitamin, vinyl ketene, borohydride exchange resin, lactam formation, aryl ketones, chiral catalysis, vinylic halides, dialkyl tartrate, chiral diamine, aryl aldehydes, organic synthesis, chiral base, organocopper reagents, porcine pancreatic lipase, allylic bromides, allylic alcohols Key Phrases - Capitalized Phrases (CAPs): (learn more)
Angew Int, Syn Commun, New York, Org Rxs, Chem Rev, Comprehensive Organic Synthesis, Chem Pharm Bull, Pure Appl Chem, Acct Chem Res, Chem Ind, Org Prep Proc Int, Rec Trav Chim, Compt Rend, Tetr Asym, Fluorine Chem, Acta Chem Scand, Academic Press, Carbohydr Res, Heterocyclic Chem, Med Chem, Bull Korean Chem Soc, Div Chem Sci, Bull Acad Sci, Organischen Chemie, Coll Czech Chem Commun New!
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forms silyl ether, cat bis, ketone diastereoselectivity, cat hydroquinone, serial cyclization, double bond transposition, cat chiral, chiral lactam, enol silane, cat vitamin, vinyl ketene, borohydride exchange resin, lactam formation, aryl ketones, chiral catalysis, vinylic halides, dialkyl tartrate, chiral diamine, aryl aldehydes, organic synthesis, chiral base, organocopper reagents, porcine pancreatic lipase, allylic bromides, allylic alcohols Key Phrases - Capitalized Phrases (CAPs): (learn more)
Angew Int, Syn Commun, New York, Org Rxs, Chem Rev, Comprehensive Organic Synthesis, Chem Pharm Bull, Pure Appl Chem, Acct Chem Res, Chem Ind, Org Prep Proc Int, Rec Trav Chim, Compt Rend, Tetr Asym, Fluorine Chem, Acta Chem Scand, Academic Press, Carbohydr Res, Heterocyclic Chem, Med Chem, Bull Korean Chem Soc, Div Chem Sci, Bull Acad Sci, Organischen Chemie, Coll Czech Chem Commun New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
28
books
cite this book:
See all 28 books citing this book
- Activated Metals in Organic Synthesis (New Directions in Organic & Biological Chemistry) by P. Cintas on 4 pages
- Perspectives in Organopalladium Chemistry for the 21st Century by J. Tsuji on page 193, and page 194
- Organic Chemistry: An Intermediate Text by Robert V. Hoffman on page 196, and page 209
- Organic Reactions (Volume 59) by Larry E. Overman on page 660, and page 685
- Principles of Asymmetric Synthesis, Volume 14 (Tetrahedron Organic Chemistry) by R.E. Gawley on page 293, and page 321
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