Computational Biology of the Heart [Hardcover]

Alexander V. Panfilov (Editor), Arun V. Holden (Editor)

Book Description

Publication Date: March 14, 1997 | ISBN-10: 0471960209 | ISBN-13: 978-0471960201 | Edition: 1

This book explores computational approaches to cardiac electrophysiology. It discusses various computational models and techniques, and applies them to visualizations and reconstructions of both normal and pathological propagation in mammalian and human hearts. Uses non-linear biological and physiological models in form and techniques of ordinary differential equations, partial differential equations and eikonal equations.

Editorial Reviews

From the Publisher

This book explores computational approaches to cardiac electrophysiology. It discusses various computational models and techniques, and applies them to visualizations and reconstructions of both normal and pathological propagation in mammalian and human hearts. The book uses non-linear biological and physiological models in form and uses techniques of ordinary differential equations, partial differential equations and eikonal equations. Reviews state-of-the-art methods. Provides readers with sufficient mathematical and computational details to use the methods in practice.

From the Back Cover

Modelling the genesis and propagation of electrical activity in the heart in quantitative terms is one of the most important recent applications of mathematical modelling in biology. The main research direction, and the most important for biological and medical applications, is the development of realistic models of electrical activity in cardiac tissue and the whole mammalian heart. Recent progress in nonlinear dynamics, advances in computer technology and experiments on cardiac tissue have made feasible the construction of such models. Computational Biology of the Heart is the first book to provide a comprehensive survey of recent research together with a systematic overview of the subject. The contributions, all written by experts in the different areas of the subject, cover all main aspects of whole heart modelling: from excitation in single cells, to two and three dimensional models of cardiac tissue and the whole heart. Various computational models and techniques are described and then applied to reconstruct and visualise modelled activity in both normal and pathological heart tissues. The models are nonlinear and use techniques of ordinary differential equations, partial differential equations and eikonal equations. The book also provides a review of modelling cardiac contraction, mapping electrical activity from electrocardiograms, and recent experimental observations of wave propagation in the whole heart. Graduate students and researchers in such areas as applied mathematical biology, clinical physiology and cardiology will find this book to be an invaluable resource for their work.

Product Details

• Hardcover: 428 pages
• Publisher: Wiley; 1 edition (March 14, 1997)
• Language: English
• ISBN-10: 0471960209
• ISBN-13: 978-0471960201
• Product Dimensions: 9.9 x 6.9 x 1.2 inches
• Shipping Weight: 1.9 pounds
• Amazon Best Sellers Rank: #3,916,263 in Books (See Top 100 in Books)