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Soft Condensed Matter Physics in Molecular and Cell Biology (Scottish Graduate Series) [Hardcover]

W.C.K. Poon (Editor), David Andelman (Editor)

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Book Description

January 13, 2006 0750310235 978-0750310239 1
Soft condensed matter physics, which emerged as a distinct branch of physics in the 1990s, studies complex fluids: liquids in which structures with length scale between the molecular and the macroscopic exist. Polymers, liquid crystals, surfactant solutions, and colloids fall into this category. Physicists deal with properties of soft matter systems that are generic and largely independent of chemical details. They are especially fascinated by the way soft matter systems can harness Brownian motion to self-assemble into higher-order structures.

Exploring the generic properties of soft matter offers insights into many fundamental questions that cut across a number of disciplines. Although many of these apply to materials and industrial applications, the focus of this volume is on their applications in molecular and cell biology based on the realization that biology is soft matter come alive.

The chapters in Soft Condensed Matter Physics in Molecular and Cell Biology originated as lectures in the NATO Advanced Science Institute (ASI) and Scottish Universities Summer Schools in Physics with the same name; they represent the thinking of seventeen experts operating at the cutting edge of their respective fields. The book provides a thorough grounding in the fundamental physics of soft matter and then explores its application with regard to the three important classes of biomacromolecules: proteins, DNA, and lipids, as well as to aspects of the biology of cells. The final section of the book considers experimental techniques, covering single molecule force spectroscopy of proteins, the use of optical tweezers, along with X-ray, neutron, and light scattering from solutions.

While this work presents fundamentals that make it a suitable text for graduate students in physics, it also offers valuable insights for established soft condensed matter physicists seeking to contribute to biology, and for biologists wanting to understand what the latest thinking in soft matter physics may be able to contribute to their discipline.

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Inside This Book (learn more)
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
soft condensed matter physics, metastable critical point, colloid dynamics, amphiphile monolayers, feasible volume, misfolded structures, stretching modulus, trap stiffness, dynamical transition, statistical potentials, filament segment, depletion interaction, backbone length, excluded volume problem, extended particle, trapped bead, intramolecular degrees, sticky edges, dividing surface, optical tweezers, scattering force, bending modulus, longitudinal fluctuations, interior point algorithm, nucleation barrier
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Chem Phys, New York, Phys Rev Lett, Proc Natl Acad Sci, Phys Chem, Eur Phys, Cambridge University Press, Daan Frenkel, Biochim Biophys Acta, Biophysical Journal, Europhys Lett, Molecular Biology of the Cell, David Andelman, Journal of Physical Chemistry, Opt Lett, Oxford University Press, Pergamon Press, Eur Biophys, Garland Science, Mechanics of the Cell, Methods Enzymol, North Holland, Proc Nail Acad Sci, References Alberts, Rev Mod Phys
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