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Conjugation-Dependent Carcinogenicity and Toxicity of Foreign Compounds, Volume 27 (Advances in Pharmacology)
 
 
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Conjugation-Dependent Carcinogenicity and Toxicity of Foreign Compounds, Volume 27 (Advances in Pharmacology) [Hardcover]

M. W. Anders (Editor), Wolfgang Dekant (Editor), J. Thomas August (Series Editor), Ferid Murad (Series Editor)

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Book Description

0120329271 978-0120329274 May 30, 1994 1
Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular basis of drug action, both applied and experimental.
Conjugation reactions have long been associated with the detoxification of xenobiotics. Recent studies suggest that Phase II reactions are an important mechanism for the bioactivation of xenobiotics.
This special volume of Advances in Pharmacology features a two-color dust jacket.

Key Features
* Summarizes the most recent information on:
* Xenobiotic conjugation
* Drug toxicity, hypersensitivity, and targeting
Chemical carcinogenesis
* Glutathione-, sulfate conjugate-, and glucuranide conjugate-dependent toxicity
* Bioactivation and bioconversion

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Editorial Reviews

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Praise for the Serial
"The book provides superb reading material which chemists and pharmacologists interested in the area of chemotherapy will surely enjoy reading."
--JOURNAL OF PHARMACEUTICAL SCIENCES

About the Author

Ferid Murad was born in Whiting, Indiana. Working concurrently on an M.D. and Ph.D. in Pharmacology, Dr. Murad graduated with both degrees from Case Western Reserve University, Cleveland, Ohio, in 1965. His many honors include the Alfred S. Maschke Award for Clinical Excellence from Case Western Reserve University in 1965. He has held several distinguished positions, including Acting Chairman in the Department of Medicine and Acting Division Chief, Division of Respiratory Medicine at Stanford University. He currently is CEO and President of Molecular Geriatrics Corporation in Lake Bluff, Illinois. Dr. Murad is married and has five children.


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Inside This Book (learn more)
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
carcinogen activation, sulfate conjugate formation, rat glutathione transferases, thioether methyltransferase, rat liver microsomal glutathione transferase, oxaprozin glucuronide, isolated rat kidney cells, free isothiocyanate, mustard glucuronide, aromatic disulphides, ethyl vinyl sulfide, ethylene dihalides, ethionine treatment, renal proximal tubular necrosis, sulfation activity, zomepirac glucuronide, mercapturic acid biosynthesis, rat kidney cytosol, acetylator rabbits, conjugate mediated toxicities, brachymorphic mice, heterocyclic arylamines, methylated aminoazo dyes, human liver cytosol, arylhydroxamic acids
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Cancer Res, Academic Press, New York, Drug Metab, Wolfgang Dekant, Kroeger Koepke, Transport Forms of Metals, Health Perspect, Glutathione Mercaptides, Bioactivation of Thiols, Acta Pharmacol, Conjugate-Based Prodrugs, Boca Raton, Cancer Inst, San Diego, Trends Pharmacol, Glutathione-Conjugate Formation, Raven Press, Life Sci, Claes Andersson, Historical Perspectives, Free Radical Biol, Karl Walter Bock, Perkin Trans, Peter Guengerich
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Front Cover | Table of Contents | First Pages | Index | Surprise Me!
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