Crystals of macromolecules have become keystones of molecular biology, bridging recombinant DNA and X-ray diffraction analysis. Protein, nucleic acid and virus crystal growth are now possible, raising hopes that virtually all macromolecules might be studied in this way. This work provides a biochemical context in which crystal growth can be pursued and instructs readers in practical aspects of the technology, laying out effective strategies for success. The underlying physical and chemical principles are presented and advances are described.
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"...should convince readers that the mysteries surrounding biomacromolecule crystallization are gradually being solved..." -- Structure
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4.0 out of 5 stars
A classic,
By TM (Arizona) - See all my reviews
This review is from: Crystallization of Biological Macromolecules (Trends in cell biology) (Paperback)
This covers pretty much every aspect of protein crystallization and is a very useful reference for students and scientists working in the field. Recommended for anyone doing protein crystallography.
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First Sentence:
The history of macromolecular crystal growth extends more than 150 years (McPherson 1991). Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
polymeric precipitants, macromolecular crystal growth, most macromolecular crystals, virus crystal growth, conventional crystal growth, satellite tobacco mosaic virus, tetragonal lysozyme crystal, conventional crystals, macromolecular crystallization, protein crystal growth, virus crystals, carboxymethylcellulose sodium salt, plant seed proteins, spiral dislocations, crystallization screen, nucleic acid crystals, lysozyme crystals, heterogeneous nucleant, multilayered stacks, precipitant concentration, preliminary crystallographic data, catalase crystals, protein crystallization, conventional small molecules, crystalline inclusion bodies Key Phrases - Capitalized Phrases (CAPs): (learn more)
Hampton Research, Crystal Screen, Courtesy of Pharmacia Corp, Nucleic Acid Crystallization Screen, Courtesy of Beckman Instruments, Courtesy of Bio-Rad Corp, Elsevier Science, Membrane Factorial Screen, Additive Screen, Class Examples, Detergent Screen, Determination of Neutral Sugars New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
The history of macromolecular crystal growth extends more than 150 years (McPherson 1991). Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
polymeric precipitants, macromolecular crystal growth, most macromolecular crystals, virus crystal growth, conventional crystal growth, satellite tobacco mosaic virus, tetragonal lysozyme crystal, conventional crystals, macromolecular crystallization, protein crystal growth, virus crystals, carboxymethylcellulose sodium salt, plant seed proteins, spiral dislocations, crystallization screen, nucleic acid crystals, lysozyme crystals, heterogeneous nucleant, multilayered stacks, precipitant concentration, preliminary crystallographic data, catalase crystals, protein crystallization, conventional small molecules, crystalline inclusion bodies Key Phrases - Capitalized Phrases (CAPs): (learn more)
Hampton Research, Crystal Screen, Courtesy of Pharmacia Corp, Nucleic Acid Crystallization Screen, Courtesy of Beckman Instruments, Courtesy of Bio-Rad Corp, Elsevier Science, Membrane Factorial Screen, Additive Screen, Class Examples, Detergent Screen, Determination of Neutral Sugars New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 4
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22
books
cite this book:
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- United Kingdom (The International Library of Politics and Comparative Government) (v. 1 & 2) by R. A. W. Rhodes in Back Matter (1), and Back Matter (2)
- The Proceedings of the First (1990 European Offshore Mechanics Symposium) by Jin S. Chung in Back Matter
- Affinity Chromatography (Chromatographic Science Series) by P. Mohr on page 100
- Affinity Chromatography by Christopher Robin Lowe on page 100
- Food Science and Food Biotechnology by Gustavo F. Gutierrez-Lopez on page 144, page 146, and page 156
- Macromolecular Crystallography, Part C, Volume 368 (Methods in Enzymology) by Charles W. Carter Jr. on page 51, page 89, and page 109
- Modern Protein Chemistry: Practical Aspects by Gary C. Howard on page 34, and page 36
- A Different Universe: Reinventing Physics from the Bottom Down by Robert B. Laughlin in Back Matter
- Solid State Physics: Advances in Research and Applications, Vol. 57 by Henry Ehrenreich on page 5
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