Curiosity Guides: The Human Genome and over one million other books are available for Amazon Kindle. Learn more
Qty:1
  • List Price: $14.95
  • Save: $3.78 (25%)
FREE Shipping on orders over $35.
Only 2 left in stock (more on the way).
Ships from and sold by Amazon.com.
Gift-wrap available.
Curiosity Guides: The Hum... has been added to your Cart
Condition: Used: Very Good
Comment: Very gently used. Pages are unmarked, and binding is tight. Minimal shelf wear. 100% Satisfaction Guaranteed! Eligible for Amazon's FREE Super Saver/Prime Shipping, Package Tracking, and 24/7 Customer Service!
Have one to sell? Sell on Amazon
Flip to back Flip to front
Listen Playing... Paused   You're listening to a sample of the Audible audio edition.
Learn more
See this image

Curiosity Guides: The Human Genome Hardcover – February 1, 2011

19 customer reviews

See all 2 formats and editions Hide other formats and editions
Amazon Price New from Used from
Kindle
"Please retry"
Hardcover
"Please retry"
$11.17
$7.52 $3.00

Save up to 40% on professional, scholarly and scientific resources.
Wiley's Summer Savings Event
Save up to 40% on professional, scholarly and scientific resources. Learn more.
$11.17 FREE Shipping on orders over $35. Only 2 left in stock (more on the way). Ships from and sold by Amazon.com. Gift-wrap available.

Frequently Bought Together

Curiosity Guides: The Human Genome + Genome: The Autobiography of a Species in 23 Chapters
Price for both: $24.91

One of these items ships sooner than the other.

Buy the selected items together


Editorial Reviews

Review

Extremely well-written. Held my interest and allowed me to understand in broad strokes the thorny and often messy field of genetic research. Having read this excellent book, I can say that the subject matter has been 98% demystified for me. And for one who spent his career in deliberate obfuscation, that's quite an achievement. --Dan Coffey, "Dr. Science"

About the Author

Dr. John Quackenbush is Professor of Biostatistics and Computational Biology, Professor of Cancer Biology, and Director of the Center for Cancer Computational Biology at the Dana-Farber Cancer Institute, and Professor of Computational Biology and Bioinformatics at the Harvard School of Public Health. Trained as a theoretical physicist, he transitioned to biomedical research through his work on the Human Genome Project.
NO_CONTENT_IN_FEATURE

Best Books of the Month
Best Books of the Month
Want to know our Editors' picks for the best books of the month? Browse Best Books of the Month, featuring our favorite new books in more than a dozen categories.

Product Details

  • Series: Curiosity Guides
  • Hardcover: 176 pages
  • Publisher: Imagine (February 1, 2011)
  • Language: English
  • ISBN-10: 1936140152
  • ISBN-13: 978-1936140152
  • Product Dimensions: 5.3 x 0.9 x 7.3 inches
  • Shipping Weight: 12.8 ounces (View shipping rates and policies)
  • Average Customer Review: 4.3 out of 5 stars  See all reviews (19 customer reviews)
  • Amazon Best Sellers Rank: #693,876 in Books (See Top 100 in Books)

More About the Author

Discover books, learn about writers, read author blogs, and more.

Customer Reviews

Most Helpful Customer Reviews

13 of 14 people found the following review helpful By danielx on August 22, 2013
Format: Hardcover
In this small book, John Quackenbush seeks to explain what the Human Genome Project (HGP) is and the implications of its findings to science and medicine. Quackenbush may have been a late-comer to biology (having received his undergraduate and graduate degrees in physics), but since the early 1990s, he has conducted research in genomics under the auspices of prominent scientific institutions, including the Dana Farber Cancer Institute. The book is aimed at a general audience, and framed in non-technical language that will be easily understood by most interested readers. Following a brief introduction, the book begins with an overview of cells, genes, and protein synthesis. Chapter 2 considers the various species for which partial or complete genetic maps now exist. Chapter 3 explores the Human Genome Project itself, and what it has and has not revealed. Chapter 4 considers causes and treatments of the broad family of cancerous diseases. Chapter 5 considers other diseases with genetic components (i.e., diabetes, cystic fibrosis, and Huntington's disease).

Chapter 6 explores fascinating issues of what can be inferred from genetics about human prehistory, including our spread out of Africa throughout the globe. Quackenbush takes pains to rebut the potential misconception that "mitochondrial Eve" and her male counterpart were the only members of their species alive at their time. Unfortunately, he endorses a more common misconception, by asserting that mitochondrial Eve and Y- chromosome Adam "were our most recent female and male common ancestors" (p. 150). The quote is incorrect. These two person were only (by definition) our most recent common ancestors by strictly matrilineal and patrilineal lines.
Read more ›
2 Comments Was this review helpful to you? Yes No Sending feedback...
Thank you for your feedback. If this review is inappropriate, please let us know.
Sorry, we failed to record your vote. Please try again
10 of 11 people found the following review helpful By curiousscientist on February 19, 2011
Format: Hardcover
This book is awesome! I was pretty nervous about reading it, feeling worried that I would not be able to understand it or that it would be written "over my head." I was so wrong. This book is written for the "average" person who is simply curious about the human genome and is interested in learning more. It brought me back to high school biology, yet it was written even more clearly than back then. This book covers the history of the Human Genome Project, the science behind it, and even the ethical implications of the project. Dr. Quackenbush has a wonderful style of writing that is both objective and clear. He is able to discuss serious ethical issues without overwhelming the reader with his own views. This book is perfect for anyone who loves science and even the budding scientist.
Comment Was this review helpful to you? Yes No Sending feedback...
Thank you for your feedback. If this review is inappropriate, please let us know.
Sorry, we failed to record your vote. Please try again
6 of 6 people found the following review helpful By Annie Gauger-Mackenzie on March 15, 2011
Format: Hardcover Verified Purchase
Oh no, not another book that is too sciencey for me to understand, I thought, when I first saw this little gem of a book. But when I picked it up I found myself drawn into a topic I know little about. Dr. Quackenbush's book makes mapping the human genome perfectly understandable. He writes of his early physics training: "I soon learned that biology was undergoing a revolution as profound as that which had occurred in physics in the late 1800s and early 1900s when... new methods of investigation set the stage for people like Niels Bohr, Erwin Schrodinger, and Albert Einstein to dramatically alter our understanding of the universe." So it is today. By combining biology, computer science, and information technology Dr. Q is able to map the human genome sequence--data that leads to "major advances in understanding, diagnosing, and treating disease." Dr. Quackenbush is a computational biologist at the Dana Farber Cancer Institute in Boston. The new technologies might actually lead to more effective treatments and managements of disease. The book is essential for both the lay person and the scientist. It also has its share of footnotes and citations, leading back to previous accretions of research. Bravo. A must have for anyone interested in understanding the evolution of cancer treatment.
Comment Was this review helpful to you? Yes No Sending feedback...
Thank you for your feedback. If this review is inappropriate, please let us know.
Sorry, we failed to record your vote. Please try again
3 of 3 people found the following review helpful By J. Ortner on April 8, 2011
Format: Hardcover Verified Purchase
It's rare when a book is written about a branch of science and a specific research project that is so important as to be seminal to the future of the Human Race. Yet here, in clear and concise language, Dr. Quackenbush, as the title aptly describes, gives us the 'essential knowledge' to understand the kind of unbelievable changes the Human Genome Project will bring to us as a species.

We are bombarded with hyperbole, often about belief systems that have no basis whatsoever in science. When a book like this is written, it's hard to underestimate its importance. Ultimately the Genomic information that he describes has the power to cure thousands of diseases, and will bring revolutions in medicine, and all aspects of biology, including horticulture, crop production, and evolution itself.

Not only does Dr Quackenbush give us the basic history of the scientific discoveries that led to the continuing success of The Human Genome Project, he reviews the biological mechanics of heredity, growth, disease, and evolution of the human race.

In the Afterward, we get to appreciate the extraordinary set of intellectual and scholarly talents that Dr Quackenbush brings to this book. He is a man of superb intellect, impressive achievements and is a respected scientist in his field. His understanding of the recent medical and technological breakthroughs, and his ability to condense and synthesize them, is why this book is such a success. This is no small task, giving the complexity and the number of different fields that were directly involved in the HGP.

I look forward to reading Dr. Quackenbush's opinions on the future of our physical bodies, the effect of the digitalization and manipulation of DNA, and what he thinks we will look like 500 years from now, and even 5,000 years from now.
Comment Was this review helpful to you? Yes No Sending feedback...
Thank you for your feedback. If this review is inappropriate, please let us know.
Sorry, we failed to record your vote. Please try again

Most Recent Customer Reviews

Set up an Amazon Giveaway

Amazon Giveaway allows you to run promotional giveaways in order to create buzz, reward your audience, and attract new followers and customers. Learn more
Curiosity Guides: The Human Genome
This item: Curiosity Guides: The Human Genome
Price: $11.17
Ships from and sold by Amazon.com