This router has solved all my home networking woes and I've had a lot of them. Granted, it's fairly complicated for a home network in that there are many devices connected both wired and wirelessly from various macs and PCs, home theater receiver, music server, network printers, network storage drives, game consoles (ps3, xbox, wii), etc. In the past I've used a combination of various routers to make things work properly. From different versions of Apple airport (express, extreme, extreme "N") to various Belkin and Linkysys models, even the supposedly foolproof WRT54G model.
The problem with the Apple airport models has been their inability to allow open NAT for Xbox Live gaming, not to mention the playstation network. I love Airport networks and their integration with OS X and all its cool file/music/drive/printer sharing and networking features but I've always had to combine an extra router to handle the non-Apple side of things. The D-Link DGL-4500 is the first router I've had that plays nice with everything on the network. It just works. It works with Apple-based networks, it provides Open NAT for Xbox Live, it works with PS3 (with some minor tweaks), and it works with just about any challenge I throw at it. Music and video streaming, latency-sensitive online gaming, you name it.
The Xtreme N gaming router is the jack of all trades. It does it all and looks great to boot. The OLED display looks sharp, has access to basic functions and status on the unit itself (a nice touch), and setup was a snap. It basically worked with everything right out of the box without much customization. The only change I made was to set the PS3 in DMZ in order to get from NAT type 3 to type 2. But Xbox 360 had open NAT out of the box. My favorite part about the DGL-4500 is the web-based interface. Although it's not exactly simplified, it is very flexible and well organized. If you have a basic understanding of designing networks, this user interface is everything you could ever ask for. The web-based interface on my previous Linksys and Belkin were all cryptic by comparison. The only thing better is Apple's own Airport utility application, but you can't win 'em all.
A small nitpick I have with the router is the bright blue power LED that shines like a beacon in a dark room. While the OLED display is just as bright, at least it shuts off after a few seconds. The power LED stays on all the time and is quite annoying if you have it setup in the bedroom, bookshelf, or on your home theater cabinet. There is no way to turn it off or turn it down. Cutting a circular piece of duct tape and taping it over solves the problem quite easily.
Although I purchased this router at an attractive price of $175, it still seems pricey for a router. I do think it's worth every penny considering that an Apple Airport Extreme "N" costs as much brand new but isn't nearly as capable or compatible. Highly recommend if you want a comprehensive, do-it-all, compatible-with-all, high-speed 802.11n router.