DNA Adducts: Identification and Biological Significance (IARC Scientific Publications) [Paperback]

K. Hemminki (Editor), A. Dipple (Editor), D. E. G. Shuker (Editor), F. F. Kadlubar (Editor), D. Segerbï¿1/2ck (Editor), H. Bartsch (Editor)

Book Description

ISBN-10: 9283221257 | ISBN-13: 978-9283221258 | Publication Date: October 6, 1994 | Edition: 1

This is the first and only handbook to provide a comprehensive review of the critical intermediates in the first step of the process of carcinogenesis. This volume reviews current knowledge of DNA adducts formed by a wide range of classes of chemical compound, including the metabolism of chemicals, mechanisms of adduction, preparation and properties of standard compounds, adduct formation in vitro, measurements of adducts in humans, and biological significance. Additional chapters review our understanding of specific types of gene damage and mutagenecity and their reaction to cancer. This volume will provide invaluable, up-to-date facts for all researchers in mechanism of carcinogenesis, toxicology, and molecular epidemiology.

Editorial Reviews

About the Author

K. Hemminki and D. Segerback are both at the Karolinska Institute, Huddinge. A. Dipple is at Frederick Cancer Research and Development Center, Frederick, Maryland. D.E.G. Shuker and H. Bartsch are both at the International Agency for Research on Cancer. F.F. Kadlubar is with the National Center for Toxicological Research, Arizona.

Product Details

• Paperback: 496 pages
• Publisher: Oxford University Press, USA; 1 edition (October 6, 1994)
• Language: English
• ISBN-10: 9283221257
• ISBN-13: 978-9283221258
• Product Dimensions: 9.4 x 6.8 x 1.1 inches
• Shipping Weight: 2 pounds
• Amazon Best Sellers Rank: #4,540,029 in Books (See Top 100 in Books)