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DNA Tumor Viruses
 
 
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DNA Tumor Viruses [Hardcover]

Blossom Damania (Editor), James Pipas (Editor)

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Book Description

0387689443 978-0387689449 December 2, 2008 1

This unique book focuses on the DNA viruses in the human population that are associated with cancers. It covers most of the viruses that are thought to contribute to human malignancy. This book represents a comprehensive review of the field of DNA tumor virology. Right now, while there are books out there that cover individual viruses that are also covered in this book, there is no single book that covers this topic comprehensively. This book is the first current, comprehensive review of its kind in the market.


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From the Back Cover

The DNA tumor viruses are central to many branches of molecular and cellular biology. This very diverse group of viruses attack common cellular pathways, which makes them powerful tools for understanding how multiple complex pathways are integrated. Additionally, the unique mechanisms employed by each viral system to alter cellular functions serve as powerful molecular probes for the identification of new targets and pathways. The scientific impact of the DNA tumor viruses extends far beyond their etiologic role in human cancers, or their contributions to our basic understanding of the cellular pathways that drive tumorigenesis. Currently, research on these viruses lies at the interface of cancer and the innate and adaptive immune response, investigating how infectious agents influence, evade, and utilize systems that regulate these processes. Thus, DNA tumor viruses serve as models for the systems biology of host-pathogen interactions.

"DNA Tumor Viruses," edited by Blossom Damania and James M. Pipas, summarizes recent advances in our understanding of this diverse and fascinating collection of viruses.


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Inside This Book (learn more)
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
polyomavirus life cycle, associated malignancies, adenovirus transformation, virus genes, clinical transplantation, infection nuclear proteins, splenic latency, virus latent origin, major latency locus, gammaherpesvirus infection, effusion lymphoma cell lines, virus nuclear protein, primary effusion lymphoma cells, adherent target cells, episome persistence, nuclear antigen leader protein, complex translational program, murine gammaherpesvirus, epithelial cell fusion, primary rat cells, multiple novel proteins, lytic switch protein, lytic reactivation, viral interferon regulatory factor, epithelial cell entry
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Proc Natl Acad Sci, Biol Chem, Mol Cell Biol, Tumor Viruses, Journal of Virology, Infect Dis, Cancer Res, Exp Med, Genes Dev, Nat Med, Springer Science, Business Media, Med Virol, Natl Cancer Inst, Clin Invest, Nucleic Acids Res, Overview of the Large, Infection of Mice, Non-coding Regulatory, Regulation of Expression, Diseases Associated, Old World, Proc Nall Acad Sci, The Life Cycle of Human Papillomaviruses, New World
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