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DNA Viruses: A Practical Approach, April 7, 2000
By A Customer
This review is from: DNA Viruses: A Practical Approach (Paperback)
DNA Viruses: A Practical Approach describes in complete detail all of the major experimental methods currently employed to study DNA viruses, from the fundamentals of virus culture to novel techniques such as surface plasmon resonance spectrometry and real-time PCR analysis of drug resistance mutations. The book begins by describing the culture of DNA viruses and the extraction, purification and characterization of virus DNA. Other topics then covered include virus genome mapping; correlation of genotype with phenotype; sequence analysis; mutagenesis of DNA virus genomes; identification and purification of proteins involved in DNA virus replication; analysis of virus replication at the molecular level; analysis of viral gene transcription and its control; identification and study of trans-acting regulatory proteins; identification, purification and characterization of viral cytokine-binding proteins; analysis of DNA virus proteins involved in neoplastic transformation; the development of DNA virus vectors for gene delivery; chemotherapy of DNA virus infections. This volume is authoritative, comprehensive and fully up-to-date. It is an essential laboratory manual and reference for all those working on DNA viruses whether in academia, industry or clinical research.
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