You can calibrate your three monitors; however, the question you need to answer is; do all three monitors have the same screen? If yes it is easy, if not you have a challenge regardless of which system you are using.
You can but it will want to re-cal periodically as monitors do change in time. It's easy to ignore the periodic prodding to redo it. People who process/print pictures, or anything else that requires rather accurate color from their monitor have the most interest in keeping up with the slow deterioration of colors.
This is what I use to sync my Dual monitor set-up and it works very well. I also calibrate other monitors and laptops in my home and I feel that it does an excellent job in bringing all the monitors very close together in color.