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In Delusional Disorder: Paranoia and Related Illnesses, Alistair Munro updates and expands on the classic literature by Emil Kraepelin and others who originally described these syndromes. He provides numerous case histories and proposes diagnostic criteria for the many subtypes of delusional disorder. Although these disorders are usually considered refractory to treatment, Munro asserts that they are responsive to treatment, particularly antipsychotic medication.
For all mental disorders, the current approach to diagnosis is limited by the need to rely on the patient's own, subjective reports and on somewhat more objective observations of the patient's behavior. The classification of mental disorders has greatly advanced as objective criteria that improve interrater reliability have been established, but we still do not understand the anatomical, pathophysiologic, or genetic bases of these disorders. Furthermore, mental disorders can often appear to be extreme versions of normal behavior. As a result, it is difficult to establish the boundaries between normality and disorder. Witness the recent debate as to whether Theodore Kaczynski, convicted of a series of deadly bombings, has paranoid schizophrenia, a delusional disorder, or (as he and some others assert) no mental disorder at all. The Kaczynski case emphasizes how the lack of biologic markers for mental diseases contributes to the debates about culpability and punishment.
Munro also argues that several syndromes that are part of a "paranoid spectrum" should be included in the category of delusional disorder. These include paraphrenia, late-onset paraphrenia, delusions of misidentification or impersonation (i.e., conviction that a familiar person is being impersonated by a stranger, also known as Capgras' syndrome), and folie a deux. The part of the book in which Munro makes these arguments is less satisfying than others and, in certain instances, confusing. The most convincing argument is for the inclusion of misidentification syndromes as a subtype of delusion disorder. The term "paraphrenia" was first used by Kraepelin to describe a condition in which there are extraordinary delusions and hallucinations but little thought disorder and better preservation of affective response than in schizophrenia. The argument for inclusion of paraphrenia stirs the long-standing controversy about the justification of a separate diagnosis for paraphrenia. Is paraphrenia one of the many subtypes of schizophrenia? Is it a schizo-affective disorder? Is it a variant of affective disorders, or is late-onset paraphrenia one of the first signs of dementing illness? Moreover, Munro himself later indicates that there is little basis for separating late-onset paraphrenia from schizophrenia. He also indicates that folie a deux is not a delusional disorder, but rather one related to delusional illnesses.
The most useful aspect of the book is its emphasis on treatment. One of the difficult problems in treating patients with delusional disorders is that they do not believe they are ill. They are absolutely convinced that their delusional system is valid and accurately reflects reality. How to get around this roadblock to treatment is a vexing issue. This book includes an excellent discussion of the patience required to help such patients accept antipsychotic medication and emphasizes the importance of minimizing side effects by starting at low dosages that are increased very gradually. Munro reviews the literature on treatment, almost all of which consists of case studies, and concludes that the antipsychotic medication pimozide is effective, since 80 percent of patients who took this drug had either a partial or a full recovery. Although this finding is very encouraging, it remains to be determined whether this response rate will be confirmed in systematic studies. Moreover, pimozide has not yet been compared directly with other antipsychotic medications, and no systematic studies have addressed the length of treatment.
Munro has done members of the medical and legal professions a service by providing a cogent synthesis of difficult material. His book will be of great interest not only to those in the mental health field but also to dermatologists, plastic surgeons, and lawyers, who often unwittingly must deal with delusional persons.
Reviewed by Craig Van Dyke, M.D.
Copyright © 2000 Massachusetts Medical Society. All rights reserved. The New England Journal of Medicine is a registered trademark of the MMS.
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Most Helpful Customer Reviews
9 of 9 people found the following review helpful:
4.0 out of 5 stars
Excellent resourse on delusional disorder,
By The Bear (USA) - See all my reviews
This review is from: Delusional Disorder: Paranoia and Related Illnesses (Paperback)
My husband has delusional disorder and I have done a lot of research and reading to better understand his disorder. He fortunately has been seeing a psychiatrist for about a year now, but with no results. After reading this book, I now have some information I can discuss with the psychiatrist to help move forward in the treatment of my husband's disorder. This book is a very good resource for better understanding delusional disorder.
12 of 14 people found the following review helpful:
4.0 out of 5 stars
Great description and classification but dehumanizing,
By
This review is from: Delusional Disorder: Paranoia and Related Illnesses (Concepts in Clinical Psychiatry) (Hardcover)
Brilliant description and classification based on an exhaustive review of the literature and a lifetime of personal clinical experience and research is somewhat marred by the author's antidynamic stand along with the really cheap shots he takes at Freud and his tendency to ridicule almost anyone who suggests that we can understand delusions in the light of the patient's conflicts and concerns. Is it really plausible that erotomanic delusions are not related to a patient's sexuality, or that litigious delusions are not rooted in a patient's hostility? Does it seem likely that there is nothing to talk about with a patient who is convinced that her stretch marks will hamper her chances for marriage? To my way of thinking this is an unfortunate dehumanization of patients with a Delusional Disorder. Highly recommended, but mainly for those who are more interested in diagnosing than in treating Delusional Disorder using other than pharmacological methods.
4 of 5 people found the following review helpful:
5.0 out of 5 stars
Thorough and enlightening but could be too clinical for a lay person,
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This review is from: Delusional Disorder: Paranoia and Related Illnesses (Paperback)
Clearly this is the work on the subject. It is a serious studious reference work. It is worth working through for anyone who has been touched by someone with this conditon.
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