Completely revised and updated, Developmental and Reproductive Toxicology: A Practical Approach, Second Edition draws together valuable information typically scattered throughout the literature, plus some not previously published, into one complete resource. In addition to the traditional aspects of developmental toxicity testing, the book covers evaluating and interpreting data. Originally titled Handbook of Developmental Toxicology, the second edition's new name reflects significant changes in its content and scope. New coverage in the Second Edition: · Genomics and proteomics · Tests for endocrine disruptors · Testing for male and female reproductive toxicity · Extensive treatment of the significance, reliability, and interpretation of developmental and reproductive toxicity data · Toxicity testing in neonatal and juvenile animals · Postnatal developmental milestones · FDA perspective on risk assessment · Extensive glossaries of developmental defect terminology Previous books on this subject have largely been academically oriented and not intended to guide the practicing developmental or reproductive toxicologist. Useful and informative, this book blends the theoretical foundation with insights gained from hands-on experience. It includes tables of comparative developmental milestones - both pre- and postnatal, glossaries of descriptive terms used in developmental toxicity evaluation, and both US and international regulatory guidelines. Bridging the gap between theory and application, this is a handy single-source of essential information to use in planning, conducting, and interpreting studies.
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Developmental toxicology has been evolving as a discipline for decades with only modest initial recognition despite the early knowledge that an excess of certain nutrients (e.g., vitamin A)' or administration of various chemicals could cause developmental defects in various animal species. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
general toxicity screen, placental peroxidase, balanopreputial separation, gestational milestones, standard open field arena, thoracic centrum, precoital interval, oocyte quantitation, ejaculatory plugs, viable litter size, bipartite ossification, conceptual tissues, maternally mediated effects, historical control database, postnatal development study, prenatal developmental toxicity study, abnormal progeny outcome, estrous cycle data, human reproductive outcomes, more test material, rabbit conceptuses, same dosage group, vaginal lavage sample, postnatal bone growth, developmental immunotoxicology Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, Environmental Protection Agency, Academic Press, Health Perspect, Boca Raton, Raven Press, Research Laboratories, National Research Council, Plenum Press, United States, San Diego, Age Size, Carnegie Inst, Toxic Substances Control Act, National Academy Press, Office of Prevention, Cancer Res, John Wiley, Office of Pesticide Programs, Life Sci, Rudimentary Agenesis, Brain Res, Human Embryology, Federal Insecticide, Marcel Dekker New!
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Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Developmental toxicology has been evolving as a discipline for decades with only modest initial recognition despite the early knowledge that an excess of certain nutrients (e.g., vitamin A)' or administration of various chemicals could cause developmental defects in various animal species. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
general toxicity screen, placental peroxidase, balanopreputial separation, gestational milestones, standard open field arena, thoracic centrum, precoital interval, oocyte quantitation, ejaculatory plugs, viable litter size, bipartite ossification, conceptual tissues, maternally mediated effects, historical control database, postnatal development study, prenatal developmental toxicity study, abnormal progeny outcome, estrous cycle data, human reproductive outcomes, more test material, rabbit conceptuses, same dosage group, vaginal lavage sample, postnatal bone growth, developmental immunotoxicology Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, Environmental Protection Agency, Academic Press, Health Perspect, Boca Raton, Raven Press, Research Laboratories, National Research Council, Plenum Press, United States, San Diego, Age Size, Carnegie Inst, Toxic Substances Control Act, National Academy Press, Office of Prevention, Cancer Res, John Wiley, Office of Pesticide Programs, Life Sci, Rudimentary Agenesis, Brain Res, Human Embryology, Federal Insecticide, Marcel Dekker New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
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