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Developmental Toxicology: Risk Assessment and the Future [Hardcover]

Ronald D. Hood (Editor)


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Editorial Reviews

From the Inside Flap

Developmental Toxicology Risk Assessment and the Future Edited by Ronald D. Hood Risk assessment in developmental toxicology is a new field that attempts to estimate the risk for developmental defects and disabilities in humans due to exposure of the parents to chemicals prior to conception, during pregnancy, or during childhood. This book reviews current knowledge of this subject and focuses on the areas of needed research that were outlined in the U. S. Environmental Protection Agency’s Guidelines for the Health Assessment of Suspect Developmental Toxicants published in 1986. Developmental Toxicology: Risk Assessment and the Future is the only up-to-date volume to cover the entire range of research and policy needs in the field. It features in-depth reviews of all major issues, presents state-of-the-art information on practical applications, and provides a comprehensive literature review. Included are experts’ analyses of these new research areas:
  • paternally-mediated effects
  • nonbehavioral functional effects
  • pharmacokinetic and physiologically-based models
  • structure-activity relationships
  • mathematical modeling
Readers will also find lucid material on mechanisms of developmental toxicity, chemical interactions, preimplantation effects, the evaluation of behavioral effects, and issues of extrapolation in behavioral teratology. In addition, there are chapters on transplacental and perinatal carcinogenesis, tests for developmental toxicity, the use of human data, the application of experimental data in risk assessment, and other important topics. Developmental Toxicology brings together, for the first time, a wealth of research findings that will be useful to scientists and administrators both in the United States and abroad. The volume is an essential working tool for individuals developing research programs or seeking funding in developmental toxicology, as well as for personnel at funding and regulatory agencies involved with improving risk assessment and regulatory decision-making in this field. --This text refers to an out of print or unavailable edition of this title.

About the Author

About the Editor RONALD DAVID HOOD is a member of the Department of Biology at The University of Alabama in Tuscaloosa, and a consultant with Ronald D. Hood and Associates, Consulting Toxicologists. He is also the author of Cacodylic Acid: Agricultural Uses, Biological Effects, and Environmental Fate (1985) as well as numerous research articles. --This text refers to an out of print or unavailable edition of this title.

Product Details

  • Hardcover: 279 pages
  • Publisher: Van Nostrand Reinhold (April 1990)
  • Language: English
  • ISBN-10: 0442004222
  • ISBN-13: 978-0442004224
  • Product Dimensions: 9.1 x 6.1 x 1.1 inches
  • Shipping Weight: 1.3 pounds

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