Diagnostic Immunopathology [Hardcover]

Colvin (Author), McCluskey (Author), Robert B. Colvin (Editor)

Book Description

Publication Date: January 15, 1995 | ISBN-10: 0781700205 | ISBN-13: 978-0781700207 | Edition: 2 Sub

Since its publication in 1988, Diagnostic Immunopathology has been one of the most important references in diagnostic pathology and clinical immunology laboratories. Now, this popular and highly acclaimed book has been updated and substantially expanded to reflect the discovery of new testing techniques and new clinical applications of immunopathology. With extensively revised contributions, 22 all-new chapters, and dozens of new color and black-and-white illustrations, the Second Edition is the most comprehensive practical guide to current techniques and their use in the diagnosis of immunopathologic diseases, immunodeficiencies, organ transplant rejection, and neoplasia. Valuable new insights into key immunopathologic mechanisms The expanded section on immunopathologic mechanisms features a detailed review of cytokines and new chapters on adhesion molecules and the complement system. The updated chapter on cell-mediated reactions describes new ways of analyzing tissue-infiltrating mononuclear cells, particularly the use of monoclonal antibodies to surface markers. An in-depth discussion of antibody-mediated reactions is also included. Expanded coverage of immunopathologic diseases and tests for autoantibodies The greatly expanded section on immunopathologic diseases includes new chapters on vasculitis, dysproteinemias, and diseases of the liver, lung, and nervous system, as well as new material on renal and skin diseases. The updated review of tests for autoantibodies now covers assays for antireceptor antibodies that cause Graves' disease and myasthenia gravis, as well as assays for more traditional autoantibodies. A new section focusing on diagnosis of AIDS and other immunodeficiencies Immunodeficiencies, which were only briefly described in the previous edition, are now discussed in depth in a separate section. This section includes a comprehensive, profusely illustrated diagnostic classification system, an updated chapter on inherited immunodeficiencies, a thorough discussion of the immunologic consequences and immunopathogenesis of AIDS, a detailed description of the key diagnostic tests for HIV-induced diseases, and new chapters on opportunistic infections and immunodeficiency-related neoplasia. A comprehensive guide to the pathology of all organ transplantations Coverage of organ transplantation, which was limited to the kidney in the previous edition, now encompasses all organs--the kidney, heart, liver, lung, pancreas, and bone marrow. This section begins with a general review of the mechanisms of allograft rejection, and then provides detailed guidelines on evaluation of allograft biopsies for each specific organ. Complete and current information on tumor markers The section on the immunohistochemistry of neoplasia includes new chapters on oncogenes, bone and skin tumors, and the molecular biology of leukemias and lymphomas, and also describes current immunohistochemical diagnostic techniques for endocrine, gynecologic, genitourina

Product Details

• Hardcover: 820 pages
• Publisher: Lippincott Williams & Wilkins; 2 Sub edition (January 15, 1995)
• Language: English
• ISBN-10: 0781700205
• ISBN-13: 978-0781700207
• Product Dimensions: 11.5 x 9 x 1.8 inches
• Shipping Weight: 5 pounds (View shipping rates and policies)
• Amazon Best Sellers Rank: #8,473,762 in Books (See Top 100 in Books)