The purpose of Diagnostic and Therapeutic Advances in Pediatric Oncology for the Cancer Treatment and Research Series is to provide an up-to-date summary of how recent advances in cancer research are being applied to the care of children with solid tumors. The interface of cancer research with clinical practice in pediatric oncology has never been more intimate than today. While researchers are identifying oncogenes and tumor suppressor genes and studying their specific functions, clinicians are using knowledge of oncogenes and tumor suppressor genes for diagnosing cancer in children, for therapeutic decision-making purposes, and for prognostic purposes. The first three chapters in the book describe models for understanding the causes of childhood cancer which were perhaps initially identified by clinicians and which are now being studied and understood by researchers. These chapters describe research evidence supporting roles for involvement of normal developmental regulatory genes in childhood oncogenesis, of abnormal immune regulation in childhood oncogenesis, and of heredity in childhood oncogenesis. The next eight chapters are devoted to descriptions of the application of new research developments to clinical practice in the most common forms of solid tumors of childhood outside the central nervous system. The final chapter describes late effects of childhood cancer and its therapy and the impact research is having on understanding and perhaps preventing these late effects. The emphasis on bridging research developments with clinical practice makes this book a unique resource for researchers and clinicians as the application of research developments to clinical practice increases and as clinical observations are studied with modern research tools.
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hone radiation, favorable histology tumors, ostcogcnic sarcoma, ectopic germ cells, pelvic patients, mediastinal germ cell tumors, ovarian germ cell tumors, hcpatoccllular carcinoma, extragonadal germ cell tumors, pulmonary radiation, intracranial germ cell tumors, intratubular germ cell neoplasia, testicular germ cell tumors, nephrogenic rests, anaplastic histology, alveolar tumors, endodermal sinus tumor, tumor locus, childhood solid tumors, cancer predisposition gene, metastatic patients, small round cell tumors, paternal isodisomy, neuroblastoma patients, malignant germ cell tumors Key Phrases - Capitalized Phrases (CAPs): (learn more)
Clin Oncol, Cancer Res, Hum Genet, Nature Genet, Med Pediatr Oncol, Cancer Genet Cytogenet, Pediatr Surg, Med Genet, Natl Cancer Inst, Proc Natl Acad Sci, Genes Chromosomes Cancer, Pediatric Oncology Group, Hum Pathol, Mol Cell Biol, Genes Dev, Surg Pathol, Hum Mol Genet, Pediatr Hematol Oncol, United States, New York, Intergroup Rhabdomyosarcoma Study, Radiat Oncol Biol Phys, Tumor Study, Children's Cancer Study Group, Mod Pathol Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
hone radiation, favorable histology tumors, ostcogcnic sarcoma, ectopic germ cells, pelvic patients, mediastinal germ cell tumors, ovarian germ cell tumors, hcpatoccllular carcinoma, extragonadal germ cell tumors, pulmonary radiation, intracranial germ cell tumors, intratubular germ cell neoplasia, testicular germ cell tumors, nephrogenic rests, anaplastic histology, alveolar tumors, endodermal sinus tumor, tumor locus, childhood solid tumors, cancer predisposition gene, metastatic patients, small round cell tumors, paternal isodisomy, neuroblastoma patients, malignant germ cell tumors Key Phrases - Capitalized Phrases (CAPs): (learn more)
Clin Oncol, Cancer Res, Hum Genet, Nature Genet, Med Pediatr Oncol, Cancer Genet Cytogenet, Pediatr Surg, Med Genet, Natl Cancer Inst, Proc Natl Acad Sci, Genes Chromosomes Cancer, Pediatric Oncology Group, Hum Pathol, Mol Cell Biol, Genes Dev, Surg Pathol, Hum Mol Genet, Pediatr Hematol Oncol, United States, New York, Intergroup Rhabdomyosarcoma Study, Radiat Oncol Biol Phys, Tumor Study, Children's Cancer Study Group, Mod Pathol Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
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