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Dipeptidyl Aminopeptidases in Health and Disease (Advances in Experimental Medicine and Biology)
 
 
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Dipeptidyl Aminopeptidases in Health and Disease (Advances in Experimental Medicine and Biology) [Hardcover]

Martin Hildebrandt (Editor), Burghard Klapp (Editor), Torsten Hoffmann (Editor), Hans-Ulrich Demuth (Editor)

Price: $154.00 & this item ships for FREE with Super Saver Shipping. Details
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Book Description

March 31, 2003 0306477173 978-0306477171 1

Proceedings of the International Conference on Dipeptidyl Aminopeptidases, held September 26-28, 2002, in Berlin, Germany.

Dipeptidyl Aminopeptidases exert a potent modulatory role at an interface between immune mechanisms, metabolic responses and neuroendocrine pathways. Experimental models and clinical studies addressing the role of these enzymes and the effect of specific inhibitors pave the way to novel therapeutic concepts in immunology, rheumatology, oncology, reproductive medicine and diabetes.

Leading experts in this field have contributed to this book which presents a state-of-the-art view on these enzymes, at a time when our understanding of their function is growing ever more rapidly and therapeutic options become imminent. The sections of the book focus on various topics:

- Structure and function of dipeptidyl aminopeptidases,
- DPP IV-like proteins,
- Immune mechanisms and immune disorders,
- Cancer and angiogenesis,
- Diabetes and metabolism,
- Therapeutic implications.


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Inside This Book (learn more)
First Sentence:
Dipeptidyl-peptidase IV/CD26 (DPPIV) is a cell-surface serine protease belonging to the prolyloligopeptidase family. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
local collagen degradation, psychoneuroendocrine function, adhesion potency, predicted beta propeller domain, denatured fibrillar collagens, serine integral membrane protease, fibroblast activation protein, hydrolyses gastric inhibitory polypeptide, atypical lymphoid cells, hydrolase domain, cell surface peptidase, insulinotropic activity, penultimate proline, insulinotropic polypeptide, glucose responsiveness, necroinflammatory activity, exopeptidase activity, gelatinase activity, prolyl oligopeptidase, overall complaints, endopeptidase activity, adhesion rate, ovarian carcinoma cells, glucose excursions, gliadin peptides
Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, Kluwer Academic, Plenum Publishers, Dipeptidyl Aminopeptidases, Proc Natl Acad Sci, Regul Pept, Biol Chem, Diabetes Care, Dipeptidvl Aminopeptidases, Dipeptidvl Peptidase, Immunol Today, Cancer Res, Deutsche Forschungsgemeinschaft, Dig Dis Sci, Clin Endocrinol Metab, Department of Biochemistry, Med Chem, Biochem Biophys Res Commun, Cell Biol, Cell Function Regulation, Cells Induced, Department of Internal Medicine, Immunol Rev, None None None None None, Novel Therapeutic Target
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