Customer Reviews

Diphenhydramine HCl 25 Mg Allergy Medicine and Antihistamine Compare to Active Ingredient of Benadryl® Allergy Generic - 400 Tablets

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Diphenhydramine is an antihistamine. It is used to block histamine release in the body. Histamine causes all manner of allergy symptoms: stuffy or runny nose, sinus inflammation, scratchy throat, itching, and hives.

Diphenhydramine is the ingredient in Benadryl, although Benadryl will cost much more than diphenydramine, since Benadryl is a brand-name drug. It is important to realize that both forms are equally equivalent in efficacy. Therefore, it makes sense to purchase the generic equivalent.

A major side effect of diphenhydramine is sedation/drowsiness. It will definately make you tired and sleepy. However, this side effect can be used as an advantage, as the medication can also be marketed as a sleeping aid. It will help you fall asleep faster and generally acts all night long. In fact, many people report a "hangover" morning effect from taking diphenhydramine the night before.

Thus, diphenhydramine has two main uses: that as an allergy medication and as a sleeping aid. Companies often add diphenhydramine to their analgesic products, such as Tylenol, to give both pain relief and a sleeping aid (Tylenol PM).

Diphenhydramine has other troubling side-effects that bear mentioning. First, is should not be used in those with narrow-angle glaucoma, or anyone with stomach problems, such as continual stomach upset or ulcers of the stomach. Second, diphenhydramine can cause a retention of urine, especially in those that have an enlarged prostate. Anyone with prostate problems should avoid diphenhydramine like the plaque. Don't take diphenhydramine with any other depressants, as the effects are additive. The same holds true for alcohol; don't take both at the same time.

The usual adult dosage is 25-50 mg, 3-4 times a day. Use the lowest effective dose to treat your symptoms. Pregnant women should avoid any antihistamines, as the medication has been known to cause birth defects.

While this is a great medication for allergies, there are better, newer antihistamines that do not produce the drowsiness that diphenhydramine does. (check out Claritin as a better, but more costly substitute).

Jim "Konedog" Koenig

My dog has allergy's(the same as we humans can get)and she also was getting rash spots due to them also until her vet told me to start giving her this,she can take it up to 3 times aday if needed.I've been doing as directed by her vet for almost 2 yrs. now and she is doing really great because of it,my sister Kim's dog also takes this for the same reasons after her vet also put her on it and has helped out greatly also.If your pet also has dry/flakey skin and scratches and their fur is dull,you need to ask your vet if your pet can take this and fish oil capsules,it also works true wonders.

I purchased this item off of Amazon thinking it was a really good deal for 400 tablets of generic Benadryl. As I was walking through my local Sam's club (Members Mark is Sam's private brand) I discovered this price is anything but good. The same exact package was on the shelf for $3.28. If you have a membership to Sam's club save yourself the time and money and purchase it there.

Also it took 7 days to get my shipment even with Amazon Prime.

The product itself is really good. It is the same active ingredient in name brand Benadryl. This is perfect for my dog who has spring/summer allergies. It works really nicely because it is in a bottle instead of the blister packs that the smaller count Benadryl packages.

I have been using diphenhydramine Hydrochloride since I discovered it when I was 16. It is a very cheap non habit forming antihistamine that doubles as a sleep inducer. I suffer from mild insomnia (my own diagnosis) and often find that I tend to be nocturnal without the aid of diphen. I also suffer from mile cat allergies and some springtime allergies as most people do. I have tried claritin d another forms of antihistamines including diphen and find that they do not make much of a difference in terms of nasal decongestion. Benadryl is an expensive name brand version of this medicine that provides no more effectiveness than the off brand so it makes no sense why anyone would pay nearly ten times as much for a small quantity of it. I continue to take diphen on week nights and find that it provides a natural drowsiness and I could not put a price on a good nights sleep but this vender certainly makes it reasonable.

Good value & reasonable ship time. Would not hesitate to use this vendor again!

Diphenhydramine HCL 25mg 400 tabs! At about a penny each, they can't be beat for Benedryl users.

take 2 of these at 8 p.m. and sleep like a baby all night long. Great value and service

Don't waste your money on Tylenol PM if you are not having any pain. The PM in Tyleno is nothing but Diphenhydramine. Buy this instead!

I was debating if I should order the name brand or generic brand. I bit the bullet and went with generic. You get more, save more, and you get the same results.

this item is a sam's club name brand. At Sam's club the price for the 400ct is $3.28! Don't waste your money.

I was going to buy these but found a bottle of 600 tabs for about $6.50 with tax at my local Costco. Wal-Mart carries them but they are priced at $4.00 for 150 tabs. Either way if you don't have a club card this is a good deal if you do best to use it.

The product is great works just like the name brand.