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Directory of Therapeutic Enzymes
 
 
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Directory of Therapeutic Enzymes [Hardcover]

Barry M. McGrath (Editor), Gary Walsh (Editor)

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Book Description

0849327148 978-0849327148 August 12, 2005 1
Carefully crafted to provide tightly focused and authoritative information, the Directory of Therapeutic Enzymes covers all approved therapeutic enzymes currently used in medicine. Written mainly by industry experts, the book includes information sourced directly from the company that developed or manufactured the product. It explores major development issues, from manufacturing and marketing to delivery of the finished product.

Chapter 1 reviews applied enzymology while chapter 2 delineates theory and applications. Between them, the first two chapters set the appropriate backdrop for the remaining chapters, which focus on actual enzyme products that have gained regulatory approval for general medical use. The chapter authors discuss the biochemistry of the enzymes, the reactions they catalyze, how they are produced or manufactured, and their medical applications.

The book highlights the many applications of approved therapeutic enzymes, including use in the treatment of blood-clotting disorders, certain cancers, and a variety of genetic disorders. Illustrated with tables and figures that support the text, the book is a single source of in-depth technical information.


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Inside This Book (learn more)
First Sentence:
Several thousand enzymes have been identified to date. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
fucosylated disialylated, directed evolution technologies, gene site saturation mutagenesis, therapeutic enzymes, drotrecogin alfa, using directed evolution, asparagine levels, excipient addition, evolution library creation, recombinant staphylokinase, placental glucocerebrosidase, directed enzyme evolution, enzyme performance, recombinant urate oxidase, bovine pancreatic deoxyribonuclease, human deoxyribonuclease, orate oxidase, working cell bank, clot surface, dornase alfa, viral inactivation steps, master cell bank, pompe disease, enzyme replacement therapy, enzyme engineering
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Care Med, United States, New York, New Engl, Humana Press, Nucleic Acids Res, John Wiley, Protein Sci, Blood Coagul, Directed Enzyme Evolution Library Creation, Marcel Dekker, Drug Resistance, Academic Press Inc, Cell Biol, Fuc Man, Trauma-Injury Infect, Trends Biotechnol, Cancer Res, Developmental History of the Enzyme, Genzyme Corporation, Pharmaceutical Enzymes, Trends Cardiovasc, Ancrod Trial, Cochrane Database Syst, Drug Deliv
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