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Discovering Genomics, Proteomics, and Bioinformatics Paperback – September 13, 2002

ISBN-13: 978-0805347227 ISBN-10: 0805347224 Edition: Bk&CD-Rom

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Product Details

  • Paperback: 352 pages
  • Publisher: Benjamin Cummings; Bk&CD-Rom edition (September 13, 2002)
  • Language: English
  • ISBN-10: 0805347224
  • ISBN-13: 978-0805347227
  • Product Dimensions: 8.5 x 0.6 x 10.8 inches
  • Shipping Weight: 1.7 pounds
  • Average Customer Review: 4.2 out of 5 stars  See all reviews (8 customer reviews)
  • Amazon Best Sellers Rank: #867,008 in Books (See Top 100 in Books)

Editorial Reviews

From the Back Cover

Discovering Genomics, Proteomics, and Bioinformatics combines integrated Web exercises with a problem-solving approach to train readers in basic hands-on genomic analysis. The authors present global problems, then provide the tools of genomic analysis to help readers dissect the answer, thus encouraging critical thinking skills. Short boxed readings called "Math Minutes" explain the math behind the biology. For anyone interested in genomics, proteomics, or bioinformatics.

Customer Reviews

4.2 out of 5 stars
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For an amature like me, I definitely need a lecture to go along with this text.
sunshine
It is amazing to realize that we still a long way to go, and what we are seeing thus far is just the beginning on a very long journey.
Amazon Customer
This book is for students who have considerable knowledge of Biology that has included basic Genetics and Genomics.
Donald L. Copeland, MD

Most Helpful Customer Reviews

33 of 35 people found the following review helpful By Amazon Customer on December 7, 2004
Format: Paperback
The sheer number of books in the area of bioinformatics is growing rapidly, and each author takes a different approach to the topic: Bergeron's Bioinformatics Computing uses concepts from Information Theory, while Pervzner's Computational Molecular Biology uses Graph Theory and Durbin et. al. Biological Sequence Analysis use Statistics and hard core mathematical analysis to get the point across. Campbell and Heyer, the authors of Discovering Genomics, Proteomics, & Bioinformatics use concepts from Electrical Engineering and Control Engineering to prescribe some of the details of genomics and proteomics. As an instructor you need to choose the right book to meet the needs and understanding level of your target audience. For biology students that have little mathematics or statistics knowledge but have taken Physics II (E&M), this would be the perfect book. The authors are a little heaving on the biological terminologies, so a sophomore level Computer Science major with little or no biology background would have a difficult time coming up to speed at the beginning, but the glossary of terms at the end of the book is comprehensive enough that can aid the learning process.

The approach to figuring out what, where and how genes are controlled using what are called circuits is simply fascinating. Genes are controlled in three ways: location of the gene, the time of control and the amount. These three metrics can easily be mapped to circuit diagram in Electrical Engineering using the concept of switches (transistors) and time varying influencers (control theory and feedback loops), the authors describe of genes are regulated. One can imagine that the process of mapping genes into circuits is a difficult task, and one would be right.
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31 of 39 people found the following review helpful By A Customer on March 21, 2003
Format: Paperback
Abstract: great and innovative book. I have seen many books, but none like this. It is still concise in this first edition, yet could become the "Lewin" of genomics.
Score: 9/10.
Recommended to students: yes, together with classic works like Brown.
Recommended to Central Library: yes.
1. The supplied CD-ROM is a nice teaching aid. Yet, it is difficult to "extract" pictures from it for teaching purposes. It would be much more useful if the pictures were individually supplied in standard high-quality graphic formats like TIFF, instead of PDF. The later is perfect for distributing text with pictures, but not to retrieve such pictures. Other publishers distribute the book artwork as individual TIFF files. That approach greatly enhances the book and boost sales. This is particularly useful for teachers. Actually, it is a must for us these days. Please, make sure that future versions of the CD-ROM or DVD-ROM are --as this one-- compatible with the open-source Unix-based Mac OS X platform. Thanks.
2. The associated web page "Instructor's Guide"<BR... is a great idea. Likewise the media menu link alerts in the book. Please, expand them.
3. The discovering questions are terrific. Please, expand them in future versions.
4. Math minutes are an excellent idea.
5. Boxes are welcome. Please, include more.
6. Also helpful are the boldface words on each chapter. Perhaps they could be also included in a keywords at the beginning of each chapter.
7. The index should be more comprehensive and should have all main entries in boldface. This is important to any index and very few books have it right.
8. The glossary is helpful. It should be more comprehensive,
including more terms.
9.
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7 of 8 people found the following review helpful By J. Estill on January 11, 2008
Format: Paperback Verified Purchase
This book follows a convoluted path to describe basic methodologies that could be taught in a much more straightforward manner. The authors get so mired down in the biology of specific applications of bioinformatic tools that the tool itself falls into the background. The poor layout of the book even makes it difficult to read. The main text of the book is interspersed with examples, "Math Minutes" and other text which are not properly set off from the main text.

The web links associated with the book are outdated and do not appear to be updated by the publisher to keep up with changes. If a web site is associated with a book, it should at the very least keep up with changes. In a quickly changing field such as bioinformatics these updates are absolutely critical.

The book is also overpriced given the low quality content and paperback binding. The figures are subpar with only purple and gray coloring. I would expect at least a few full color figures for a book at this price point.

Overall I would say that this book is not a useful tool for teaching bioinformatics or genomics.
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9 of 12 people found the following review helpful By John Matlock on March 16, 2006
Format: Paperback
This book represents a breakthrough in textbook design. It starts with a 'case study' for a child visiting you the physician. You get the basic symptoms from the mother, then you are sent to the web to go attempt to establish a diagnosis. And you are not sent to some private web site, but to the Online Mendelian Inheitance in Man (OMIN) database of human diseases and genes, and to the National Center for Biotechnology Information. Immediately the student is exposed to a wealth of information far beyond what any book could provide. It's rare that you see a textbook that attempts to take the student into the real world.

Intermixed with the case studies is textual materials that provide the student with the basic background that they need. In addition there are almost random Math Minutes and Discovery Questions that direct the student into further depth of understanding.

If you are planning to teach this kind of class, you owe it to yourself to at least investigate this book before selecting a text.
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