Customer Reviews

Prion Diseases and Copper Metabolism BSE,Scrapie, and CJD Research

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This is a very well researched and prepared book on the neurodegenerative conditions known as prion diseases or TSEs. It focuses on a particular aspect, the metal binding capacity of the protein at the heart of these diseases, the prion protein. As such this finding links the research to the many other neurodegenerative diseases that have also been linked to metals. These diseases include Alzheimers and Parkinsons disease. This is brought out in the book. David Brown had been at the forefront of this kind of research for many years and his sections of the book are clearly the best. Contributions from other authors are also present and good. Unlike other books on this subject, this one is refreshingly unbiased and remains an up-to-date account of the field. It is very molecular which makes it more like "hard science" too many of these books are filled with hundred of pages of brain sections or descriptions of how the researchers extrapolate from dead mice to human disease. If you want an introduction to the prion diseases as a student or are a professional looking for a readable and relevant update - this is the book for you!!
PS: By the way my copy is a hardback!!!