The present volume of Current Topics in Microbiology and Immunology contains seven chapters that illuminate various aspects of a protein's genesis and terminal fate in the endoplasmic reticulum (ER). This area is of immediate medical relevance since the malfunctioning of proper quality control during protein synthesis, and the lack of sufficient degradation of improper proteins from the ER forms the basis of many human diseases. The study of viruses and bacteria has significantly contributed to the understanding of the processes going on at the ER membrane, which is illustrated in several chapters of the volume. The field of protein degradation from the ER touches upon many other fields of cell biology, such as immunology, pathology, microbiology, and embryology.
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Key Phrases - Statistically Improbable Phrases (SIPs):
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misfolded secretory protein, lumenal substrates, protein dislocation, recognizes sugar chains, protein quality control, malfolded proteins, endoplasmic reticulum degradation, autocrine motility factor receptor, unfolded protein response, associated protein degradation, reticulum quality control, misfolded glycoproteins, chaperone requirement, folding efficiency, ubiquitination machinery, cytosolic substrates, misfolded proteins, peptide export, luminal protein, cytosolic proteasomes, other peptidases, endoplasmic reticulum proteins, ubiquitin ligase activity, protein disulfide isomerase, bleomycin hydrolase Key Phrases - Capitalized Phrases (CAPs): (learn more)
Biol Chem, Cell Biol, Mol Biol Cell, Mol Cell, Proc Natl Acad Sci, Curr Biol, Trends Biochem Sci, Annu Rev Cell Dev Biol, Springer-Verlag Berlin Heidelberg, Annu Rev Biochem, Biochem Biophys Res Commun, Biochim Biophys Acta, Cell Sci, Dev Cell, Exp Med, Genes Dev, Nat Immunol, The Journal of Biological Chemistry, Cancer Res, Proc Nall Acad Sci, Ann Neurol, Cell Mol Life Sci, Clin Invest, Hum Mol Genet, Nat Med New!
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misfolded secretory protein, lumenal substrates, protein dislocation, recognizes sugar chains, protein quality control, malfolded proteins, endoplasmic reticulum degradation, autocrine motility factor receptor, unfolded protein response, associated protein degradation, reticulum quality control, misfolded glycoproteins, chaperone requirement, folding efficiency, ubiquitination machinery, cytosolic substrates, misfolded proteins, peptide export, luminal protein, cytosolic proteasomes, other peptidases, endoplasmic reticulum proteins, ubiquitin ligase activity, protein disulfide isomerase, bleomycin hydrolase Key Phrases - Capitalized Phrases (CAPs): (learn more)
Biol Chem, Cell Biol, Mol Biol Cell, Mol Cell, Proc Natl Acad Sci, Curr Biol, Trends Biochem Sci, Annu Rev Cell Dev Biol, Springer-Verlag Berlin Heidelberg, Annu Rev Biochem, Biochem Biophys Res Commun, Biochim Biophys Acta, Cell Sci, Dev Cell, Exp Med, Genes Dev, Nat Immunol, The Journal of Biological Chemistry, Cancer Res, Proc Nall Acad Sci, Ann Neurol, Cell Mol Life Sci, Clin Invest, Hum Mol Genet, Nat Med New!
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Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 17
books:
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books
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- Antibodies in Viral Infection (Current Topics in Microbiology and Immunology) by Dennis R. Burton in Back Matter
- Cellular Factors Involved in Early Steps of Retroviral Replication. Current Topics in Microbiology and Immunology, No. 281 by John A.T. Young in Back Matter
- Immunology and Immunopathogenesis of Malaria (Current Topics in Microbiology and Immunology) by Jean Langhorne in Back Matter
- Chronic Lymphocytic Leukemia (Current Topics in Microbiology and Immunology, No. 294) by Federico Caligaris-Cappio in Back Matter
- Quasispecies: Concept and Implications for Virology (Current Topics in Microbiology and Immunology) by Esteban Domingo in Back Matter
See all 17 books this book cites
- Current Concepts in Autoimmunity and Chronic Inflammation (Current Topics in Microbiology and Immunology) by Andreas Radbruch in Back Matter
- Chemokines and Viral Infection (Current Topics in Microbiology and Immunology) by Thomas E. Lane in Back Matter
- Reoviruses: Entry, Assembly and Morphogenesis (Current Topics in Microbiology and Immunology) by Polly Roy in Back Matter
- Hepatitis Delta Virus (Current Topics in Microbiology and Immunology) by John L. Casey in Back Matter
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