Rett Disorder and the Developing Brain (Oxford Medical Publications) [Hardcover]

Alison Kerr (Editor), Ingegerd Witt Engerstrï¿1/2m (Editor)

Book Description

ISBN-10: 0192630830 | ISBN-13: 978-0192630834 | Publication Date: April 26, 2001 | Edition: 1

Rett disorder, first described by Andreas Rett in 1966, is a condition which involves the functions on which intelligence and expression depend. It is probably the most common genetic disorder encountered in profoundly intellectually disabled females. Its many manifestations include epilepsy, scoliosis, nutritional difficulties, and disorders of mood and movement. This book provides an up-to-date account of current research into the disorder at a time when the causative mutations have just been discovered on the MeCP2 gene. The first section of the book presents the clinical signs and the latest research into the genetic, neuro- anatomical and neuro-chemical aspects of Rett disorder. The second section moves on to deal with the neuro-physiological research, concentrating on the autonomic system, which is deeply implicated in the disease mechanisms. The final section of the book examines the behavioural and psychological features of Rett disorder and discusses issues relating to communication. The chapters are written by a distinguished, international team of experts, all currently active in research. The contributions bring our understanding of the Rett disorder right up-to-date, as the study of the condition moves from an era of description into a time when there are real possibilities for beneficial interventions.

Editorial Reviews

Review

"This book will be a valuable guide for clinicians and researchers of human disease in various specialities - paediatrics, genetics, neurology, neurochemistry, neuropathology, neurophysiology, brain imaging, psychiatry, and psychology - and allow them to engage in future research not only of Rett disorder but also of other early developmental disorders. Clinicians, educators, therapists, and families of people affected by this enigmatic disorder who wish to understand more of its problems will benefit from the knowledge this book contributes to advice and management."The Lancet

`This book will be a valuable guide for clinicians and researchers of human disease in various specialities - paediatrics, genetics, neurology, neurochemistry, neuropathology, neurophysiology, brain imaging, psychiatry, and psychology - and allow them to engage in future research not only of Rett disorder but also of other early developmental disorders. Clinicians, educators, therapists, and families of people affected by this enigmatic disorder who wish to understand more of its problems will benefit from the knowledge this book contributes to advice and management.' The Lancet

About the Author

Dr Alison Kerr Department of Psychological Medicine Gartnavel Royal Hospital 1055 Great Western Road Glasgow G12 0XH Tel: [phone] Fax: [phone] E-mail: [e-mail] Dr Ingegerd Witt Engerstrom Swedish Rett Centre Mjallebacken PO Box 601 S-83 223 Froson SWEDEN E-mail: [e-mail]

Product Details

• Hardcover: 400 pages
• Publisher: Oxford University Press, USA; 1 edition (April 26, 2001)
• Language: English
• ISBN-10: 0192630830
• ISBN-13: 978-0192630834
• Product Dimensions: 9.4 x 6.6 x 1.1 inches
• Shipping Weight: 2 pounds
• Amazon Best Sellers Rank: #6,730,800 in Books (See Top 100 in Books)