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230 of 235 people found the following review helpful
on June 1, 2012
My husband has a blood clotting disorder and was placed on Coumadin for life. He wasn't doing well on Coumadin. There was so many nasty side effects so we looked for an alternative to Coumadin. This supplement was recommended to us 10 months ago. He is doing so much better since taking Nattokinase. He is off of Coumadin (without his Dr's blessing), it has brought his cholesterol down, brought his blood pressure down (along with vitamin C), and improved his cataracts. He just had an eye exam and his eye glasses prescription was the same as two and a half years ago. That has NEVER happened. His eyes have always gotten worse for every exam. His Dr wasn't happy with him when he got off of Coumadin, but he is happy with the results and can't believe hubby is off of cholesterol and high blood pressure meds. He has never see that happen in his patients. We are excited to see other benefits pop up in the future.
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155 of 160 people found the following review helpful
Nattokinase is currently being studied as an effective way to dissolve fibrin and thrombus (blood clots) in study animals (usually rats) as well as in humans. As someone who has suffered and endured more DVTs (Deep Venous Thrombosis) than can be counted across a couple decades and suffers from virtually all the possible complex complications stemming from multiple complete occlusions (including Post Thrombotic Syndrome (PTS), May Thurner Syndrome (MTS), Chronic Venous Insufficiency (CVI), chronic lymphedema and veins that have become destroyed from too many years of warfarin therapy - never again, no matter what, my body simply cannot tolerate the inflammation from warfarin anymore...) finding an effective way to both PREVENT as well as DISSOLVE blood clots is vital for my quality of life.

The many medical professionals I have consulted over the years never explained a basic concept to me - today's oral anti-coagulation therapies are ONLY designed to "prevent" further DVT (which is really ironic considering I always develop extensive new clotting while on warfarin therapy!) There are NO oral medications for "dissolving" existing blood clots OR fibrin which is vital to preventing further complications such as those from which I suffer and have endured. Thankfully for various reasons I was never a good candidate for any of the invasive procedures being tried over the years - whether bypass the MTS, or vena cava filters nor stenting as is being tried in recent years - they all seem to all too frequently cause further cascading series of events that are often very detrimental to quality of life.

I have incorporated nattokinase into my supplement regimen the past few years on a periodic basis as I can afford with obvious success; this is called evidence based experience. Despite having multiple diagnosis leaving me permanently disabled and my leg rather disfigured, *all* of my medical professionals (including a podiatrist, interventional radiologist, vascular surgeons, cardiologists, hematologists, etc) are stunned at how healthy my leg appears DESPITE my very well documented medical saga. Yes, my leg is still obviously disfigured and likely always will be, but the skin appearance is visibly improving and healthier as compared to others suffering a similar set of complex diagnosis stemming from chronic recurrent DVTs.

The supplements that go well with nattokinase for leg vein health after DVT include: fish oil, flax seed oil, a whole food sourced multi such as New Chapter Every Woman's One Daily, 72 Count, vitamin D, vitamin K2/mk7 (only if NOT taking warfarin!), B vitamins such as NOW Foods B-12,Liquid B-Complex, 8 ounce, magnesium, horse chestnut, garlic, parsley, as well as red wine as explained to me by a D.O. whom I consulted a couple years ago. The medical professionals generally cannot offer alternatives but will discuss their virtues when asked! Keep in mind if you have any chance of getting "real" information from medical professionals, only have these discussions when storm troopers (pharmaceutical reps) are not around; watch for those all too frequent catered lunches they tend to provide to the most indoctrinated...
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129 of 135 people found the following review helpful
on October 6, 2011
I take Nattokinase along with the Serrapeptase( hope spelling is right).
every morning and I've not felt this great in a long time nor did I ever have an active lifestyle.

I feel refreshed everyday all day and in always a great mood; alot of suppplements I used take I've
stopped taking because of this amazing product.

No longer feel like a slugg, I feel like a very healthy woman!!!
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158 of 167 people found the following review helpful
on October 12, 2012
I felt obligated to write a review about "Doctor's Best Best Nattokinase (2, 000 Fu)" because the improvement my family felt over last 2 years. You are right, 2 years, which qualifies me to write a meaningful review on it.

Why did my family start to use it? My father had a heart attack two and a half years ago. The ECG & MRI diagnoses were not good and he also had Embolism. With traditional treatment, I started looking for additional supplements that could help. After some research, I found Nattokinase could be one choice and "Doctor's Best" is quite reputable with very reasonable price. So everything happened there.

What is the benefit? The improvement is STEADY and HUGE. AFTER CONSULTING THE DOCTOR, my father started taking the 2k Fu pills everyday. Because some worries about potential risks (see below), I asked him to take 1 pill a day in warm seasons and 2 pills a day in cold seasons, and asked him to regularly do the blood tests. After 1 year, the ECG result showed an improved T-wave from -4 to -3 (I'm not professional and the numbers are direct readings from the ECG curve which was explained by the doctor "a good sign of improvement"). And last week, after 2 years of taking the pills, the T-wave is lifted from -3 further to -2 plus significant improvement in body feeling. According to the doctor, this is GREAT!

What is the other benefit? I started to take it about 1 year ago because my blood pressure is a bit high and I know my blood is very viscous. I constantly monitored my blood pressure afterwards and found that it decreased from average low@86~high@131 to low@75~high@119 in about a year. I'm not taking any other blood pressure control pills and my diet habit is the same. So this is definitely due to Nattokinase. And I'm happy about it.

What are the RISKS? While doing the research before buying, I noticed there is a scientific paper (published) discussed the improvement of blood mobility (reduction of viscosity) after treatment of Nattokinase (many adults were taking the pills and their blood samples were tested over some time period). And then there are reports stating that longer time is needed to stop bleeding and unexpected bleeding occurs while some people brushing the teeth after taking Nattokinase. So I think there must be risks about it. And indeed, my mom can't take it because several days of Nattokinase intake would always cause her teeth to bleed after brushing. So for those who have this kind of problem, be careful. The best way is to always consult your doctor before taking and when anything unusual happened after taking.

In summary,
Pro: It worked in my cases; Pills are small; "Doctor's Best" is a good brand.

nothing really bad, you just need to know if it fits you.
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119 of 127 people found the following review helpful
on September 30, 2011
My wife, 63, has been taking Nattokinase -- two per day -- for the last six to eight weeks. It seems to decrease the systolic pressure by 10 to 20 points and the diastolic pr by about 5 to 8 points. We have tried to test that by her skipping it for a day or two and BP rises back to its old level. She is able to take this (or any such) supplement only when it is truly vegetarian and we are glad that the Dr Best's brand has it available.
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70 of 75 people found the following review helpful
on March 23, 2010
This product is Fantastic! I bought Nattokinase for my Mother who has high blood pressure. Within a few weeks of taking 2 pills a day, her BP has dropped down to safety! Highly recommend this item!
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64 of 70 people found the following review helpful
on January 27, 2009
Lowered my cholesterol 30 pts in 2 months . ANyone can take enzymes except those on cumadin
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50 of 54 people found the following review helpful
on March 8, 2013
I had a stroke which injured my brain and caused a serious personality problem . My problem appeared to be permenant and Terrminal , I took a regiment of Nattokinase , and Serrapeptase , along with Niacinamide all bought from Amazon . I exercised and now my full memory has returned and my personality is just like when I was young , and There is no longer any sign of brain damage . I am very thankful to be alive and well at age 65 . For me these supplements saved me from a Terminal illness .
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31 of 32 people found the following review helpful
on April 14, 2014
I purchased Nattokinase 2,000 Units and Serrapeptase 120,000 Units in January 2014 when the doctor told me that I had 7 fiborids between 1 inch and 3 inches in diameter. The doctor told me on dec 31, 2013.
I had another ultrasound on March 26, 2014. At that time my doctor called me and said that I now have 3 fibroids and the 3 remaining fibroids are half the size of what they were originally on Dec. 31st. These Products are AMAZING!!!
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36 of 39 people found the following review helpful
on July 11, 2012
I have always been a fan of Nattokinase and Doctor's Best is a decent brand, although there are more potent and higher quality brands around in my opinion. This is coming from a guy who first ordered Nattokinase from the company in Japan tied to the doctor that discovered the enzyme (that package even arrived with Japanese labeling and a little card inside with English instructions). That product was incredible; so much so that you could feel a tingling-relaxed sensation that apparently had something to do with the blood being oxygenated more efficiently or something. I remember having very restful sleep as well as lower blood pressure and just a very relaxing feeling overall. I've never experience that to the same level with the Doctor's Best brand, but I've read some independent studies that affirm it has adequate potency, especially for the price. Unfortunately, I have no idea how to get in contact with the company I used to order from in Japan. I would love to buy it again. In the meantime though, this is a good brand and I appreciate Amazon's auto ship options. I am happy with my order.
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