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Drug Delivery: Engineering Principles for Drug Therapy (Topics in Chemical Engineering) [Hardcover]

W. Mark Saltzman (Author)

3.0 out of 5 stars See all reviews (1 customer review) |

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Book Description

ISBN-10: 0195085892 | ISBN-13: 978-0195085891 | Publication Date: March 15, 2001 | Edition: 1

Synthetic materials are a tremendous potential resource for treating human disease. For the rational design of many of these biomaterials it is necessary to have an understanding of polymer chemistry and polymer physics. Equally important to those two fields is a quantitative understanding of the principles that govern rates of drug transport, reaction, and disappearance in physiological and pathological situations. This book is a synthesis of these principles, providing a working foundation for those in the field of drug delivery. It covers advanced drug delivery and contemporary biomaterials.

#outer_postBodyPS { display: none; } #psGradient { display: none; } #psPlaceHolder { display: none; } #psExpand { display: none; } Synthetic materials are a tremendous potential resource for treating human disease. For the rational design of many of these biomaterials it is necessary to have an understanding of polymer chemistry and polymer physics. Equally important to those two fields is a quantitative understanding of the principles that govern rates of drug transport, reaction, and disappearance in physiological and pathological situations. This book is a synthesis of these principles, providing a working foundation for those in the field of drug delivery. It covers advanced drug delivery and contemporary biomaterials.

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Editorial Reviews

Review

"Providing a working foundation in the principles underlying drug transport, reaction, and disappearance in physiological and pathological situations, this introduction and guide covers a range of topics, including drug and protein properties, drug modification and diffusion, and polymeric biomaterials. Case studies, physiological guidelines, and useful nomenclature and data are also featured. Saltzman teaches chemical engineering at Cornell University."--SciTech Book News

"[A]n excellent addition to the library of any scientist interested in drug delivery systems. Unlike others in the area, this volume is focused on quantitative understanding of the principles that govern rates of drug transport, reaction, and disappearance in physiological conditions. ... even a scientist who may lack a background in mathematics could benefit from this unique discussion of engineering concepts. ... what makes this book outstanding is the ability of the author to discus mathematical equations grounded in real examples. ... The book is highly recommended as a textbook in the field of drug delivery ..."--The Quarterly Review of Biology

About the Author

W. Mark Saltzman is at Cornell University.

Product Details

Hardcover: 384 pages
Publisher: Oxford University Press, USA; 1 edition (March 15, 2001)
Language: English
ISBN-10: 0195085892
ISBN-13: 978-0195085891
Product Dimensions: 9.4 x 6.1 x 1.1 inches
Shipping Weight: 1.4 pounds (View shipping rates and policies)

Average Customer Review: 3.0 out of 5 stars See all reviews (1 customer review)

Amazon Best Sellers Rank: #167,891 in Books (See Top 100 in Books)
- #1 in Books > Medical Books > Pharmacology > Drug Delivery Systems

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3.0 out of 5 stars Nothing Exciting, February 1, 2011

itkuo (Philadelphia, PA) - See all my reviews

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This review is from: Drug Delivery: Engineering Principles for Drug Therapy (Topics in Chemical Engineering) (Hardcover)

It is not a textbook with many fancy figures or even DVD, but still worth buying if you are registered for a Drug Delivery course. The concepts in this book are pretty clear, and the book itself is not too heavy to carry, either.

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Inside This Book (learn more)

First Sentence:
Humans have always attempted to improve their health by ingesting or administering drugs. Read the first page

Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
accessible porosity, interstitial delivery, matrix delivery systems, tortuosity values, protein diffusion coefficients, extracellular volume fraction, brain interstitium, frictional drag coefficient, reduced diffusion coefficient, facilitated transport systems, physiological pharmacokinetic models, lower reproductive tract, percolation concepts, critical porosity, bolus delivery, drug modification, hindered transport, probe diffusion, drug movement, polymeric biomaterials, mutual diffusion coefficients, tracer diffusion coefficient, polymer implant, drug molecules, total artificial heart

Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, Biophysical Journal, Cancer Research, Chemical Engineering Science, Oxford University Press, Journal of Controlled Release, Journal of Pharmaceutical Sciences, Brain Research, Pharmaceutical Research, Academic Press, Nature Biotechnology, American Journal of Physiology, John Wiley, Journal of Biomedical Materials Research, Marcel Dekker, New England Journal of Medicine, Bioconjugate Chemistry, Journal of Chemical Physics, Journal of Membrane Science, Alza Corp, Biophysical Chemistry, Boca Raton, Critical Reviews, Experimental Neurology, Journal of Neuroscience

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Books on Related Topics | Concordance | Text Stats

Citations (learn more)

This book cites 50 books:

Transport Phenomena, 2nd Edition by R. Byron Bird on 4 pages
The Mathematics of Diffusion by John Crank on page 47, page 109, and page 275
Polymeric Biomaterials, Revised and Expanded by Severian Dumitriu in Back Matter (1), Back Matter (2), and Back Matter (3)
Biodegradable Polymers as Drug Delivery Systems (Drugs and the Pharmaceutical Sciences) by Mark Chasin on page 278, Back Matter (1), and Back Matter (2)
Receptors: Models for Binding, Trafficking, and Signaling by Douglas A. Lauffenburger on page 48, page 110, and page 156

See all 50 books this book cites

4 books cite this book:

Tissue Engineering: Engineering Principles for the Design of Replacement Organs and Tissues by W. Mark Saltzman on 8 pages
Cellular Drug Delivery: Principles and Practice by D. Robert Lu on page 22
Levine's Pharmacology: Drug Actions and Reactions, Seventh Edition (PHARMACOLOGY- DRUG ACTIONS & REACTIONS (LEVINE)) by Carol T. Walsh on page 111
Introduction to Biomedical Engineering, Second Edition by John Enderle on page 315

Books on Related Topics (learn more)

Drug Delivery by Binghe Wang

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Handbook of Pharmaceutical Controlled Release Technology by Donald L. Wise

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Comparative Pharmacokinetics by J. Edmond Riviere

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Mechanisms of Transdermal Drug Delivery by Russel O. Potts

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