New Drug Discovery and Development [Hardcover]

Daniel Lednicer (Author)

Book Description

Publication Date: October 20, 2006 | ISBN-10: 0470007508 | ISBN-13: 978-0470007501 | Edition: 1

A case history approach to drug synthesis and discovery

Discover the origins of some of today’s most popular drug therapies. Explore case histories and gain insight into major classes of antibiotics, antiviral drugs, analgesics, steroids, compounds designed to lower cholesterol, and more. Review the steps required for FDA approval.  This is a great reference for students in medicinal chemistry, researchers in pharmaceuticals, and medical practitioners.

Editorial Reviews

Review

"...a useful addition to the literature on the history of drugs." (Pharmacy in History, Vol. 49 (2007) No. 1)

"...a very enjoyable trip through pharmaceutical history." (Journal of Medicinal Chemistry, April 5, 2007)

From the Back Cover

A case history approach to drug synthesis and discovery

Discover the origins of some of the most popular drug therapies on the market today, including penicillin, Minoxidil, Viagra®, and "the pill." This guide to drug synthesis and discovery focuses on case histories. Organized by drug category, the guide introduces readers to the rich interplay of research and serendipity that is responsible for many commonly prescribed drugs today. Moreover, the author demonstrates how the discovery and development of a new drug or drug category creates a domino effect, leading to the development of newer therapeutics as pharmaceutical companies compete to satisfy market demands.

Readers gain new insight from both a chemical and medical perspective into:

• Major classes of antibiotics used to treat infectious diseases
• Antiviral drugs, including recent antiviral compounds designed to take advantage of new findings concerning the molecular biology of viral infection
• Growth of several classes of analgesics
• Intricate chemical structure of steroids
• Development of compounds designed to lower cholesterol
• Discovery of COX-2 nonsteroidal anti-inflammatory drugs (NSAIDs)
• Research and development of oral contraceptives

The text ends with an overview of the many steps required before a drug may be approved by the U. S. Food and Drug Administration.

Lavishly illustrated with chemical structures, and supplemented by an appendix for those readers who need assistance in interpreting the structures, the text is highly suited for students in medicinal chemistry, as well as for researchers in pharmaceuticals and medical practitioners in search of new insights into drug synthesis and discovery.

See all Editorial Reviews

Product Details

• Hardcover: 190 pages
• Publisher: Wiley-Interscience; 1 edition (October 20, 2006)
• Language: English
• ISBN-10: 0470007508
• ISBN-13: 978-0470007501
• Product Dimensions: 6.4 x 0.7 x 9.3 inches
• Shipping Weight: 15.2 ounces (View shipping rates and policies)
• Amazon Best Sellers Rank: #2,683,015 in Books (See Top 100 in Books)

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