Drug-Drug Interactions: Scientific and Regulatory Perspectives, Volume 43 (Advances in Pharmacology) [Hardcover]

Albert P. Li (Editor), J. Thomas August (Series Editor), Ferid Murad (Series Editor), M. W. Anders (Series Editor), Joseph T. Coyle (Series Editor)

Book Description

Publication Date: October 16, 1997 | ISBN-10: 0120329441 | ISBN-13: 978-0120329441 | Edition: 1

Drug–Drug Interactions is a comprehensive review of the scientific and regulatory perspectives of drug–drug interactions from the point-of-view of academia, industry, and government regulatory agencies. This book is intended for professionals in the pharmaceutical industry, health care, and governmental regulatory agencies. Topics of interest include the mechanistic understanding of drug–drug interactions, the prediction of drug–drug interaction potential of new drugs, and the avoidance of clinically significant drug–drug interaction in patients.

Key Features
* Provides useful references on the science of drug-drug interactions
* Describes in a basic and comprehensive manner drug-drug interactions from the mechanistic viewpoint
* Contains original data from academic and industrial laboratories
* Presents an overview of regulatory agency positions

Editorial Reviews

Review

Praise for the Series
"Recommended not only to pharmacologists but also to all those in related disciplines."
--NATURE
"The works do represent an extensive compilation of recent data by outstanding researchers in this area. They are generally scientifically excellent, the bibliographies are good, and the individual reports are clear, concise, and extremely well illustrated."
--H.E. Kaufmann in CHEMOTHERAPY
"Superb reading material."
--JOURNAL OF PHARMACEUTICAL SCIENCES
"This book represents a comprehensive review of drug-drug interaction and is unique since the contributors are from all facets of the workplace, including academic institutes, government, and industry... The most attractive feature of the book is its well-focused subject area with the emphasis on the importance of P-450 enzymes in drug interactions and how government regulatory agencies evaluate them... It is unique since it presents the regulatory aspects of drug evaluations as an integral part of the science of drug-drug interactions."
--Rajendar Mehta, PhD, University of Illinois at Chicago College of Medicine for DOODY'S PUBLISHING

From the Back Cover

Praise for the Series
"Recommended not only to pharmacologists but also to all those in related disciplines."
--NATURE
"The works do represent an extensive compilation of recent data by outstanding researchers in this area. They are generally scientifically excellent, the bibliographies are good, and the individual reports are clear, concise, and extremely well illustrated."
--H.E. Kaufmann in CHEMOTHERAPY
"Superb reading material."
--JOURNAL OF PHARMACEUTICAL SCIENCES
This volume represents a comprehensive review of drug-drug interactions from the perspectives of academia, industry, and government regulatory agencies. The topics covered include drug metabolism enzymes, toxicology, in vitro mechanistic approaches, and the regulatory perspectives of drug-drug interactions. Drug-Drug Interactions: Scientific and Regulatory Perspectives is intended for professionals in the pharmaceutical industry, in health care, and in governmental regulatory agencies who are interested in understanding the mechanisms of drug-drug interactions, predicting the interaction potential of new drugs, and avoiding clinically significant drug-drug interactions in patients. It should also be of interest to students and researchers in the areas of pharmacology, toxicology, pharmacokinetics, and medicine.

See all Editorial Reviews

Product Details

• Hardcover: 304 pages
• Publisher: Academic Press; 1 edition (October 16, 1997)
• Language: English
• ISBN-10: 0120329441
• ISBN-13: 978-0120329441
• Product Dimensions: 9 x 6.1 x 0.8 inches
• Shipping Weight: 1.4 pounds (View shipping rates and policies)
• Amazon Best Sellers Rank: #10,624,830 in Books (See Top 100 in Books)