Duchenne Muscular Dystrophy (Oxford Monographs on Medical Genetics) [Hardcover]

Alan E. H. Emery (Author)

Book Description

Publication Date: January 1, 1993 | ISBN-10: 0192623702 | ISBN-13: 978-0192623706 | Edition: 2

This is the second edition of a highly acclaimed monograph. It is currently the only book which considers Duchenne Muscular Dystrophy (DMD) in detail and critically evaluates the extensive published literature. The author draws on his extensive clinical experience and scientific knowledge to provide an account of one of the most common inherited diseases. After a brief historical introduction, he describes the clinical features of the disease, emphasizing the involvement of tissues other than skeletal muscle. The biochemistry, genetics, and molecular pathology are discussed in the context of recent research findings, building a picture of the role of dystrophin in the pathogenesis of the disease. Prevention through neonatal screening, carrier detection, genetic counseling, and prenatal diagnosis is covered extensively, stressing the importance of DNA markers and gene probes. Finally, the book discusses the management of patients with the disease and the possibilities for treatment, which include surgical correction of deformities, new drug treatments, the prospects for myoblast transfer, and the possibilities for gene therapy.

Editorial Reviews

Review

'With the same fluency and flow which he achieved in the first edition, Alan Emery has succeeded in a masterly fashion in assimilating and digesting the essentials from all this new information and integrating it into this new volume. Once again he has comprehensively covered the whole field. His vast personal experience both as a geneticist and a clinician are clearly apparent from the confidence as well as the sensitivity with which he has covered many of the topics. This book should find a wide appeal ... both as a source of reference as well as an interesting and informative read.' Victor Dubowitz, Royal Postgraduate Medical School. London, Neuromuscular Disorders, Vol. 3, No. 2, 1993

'This book is an excellent review of the history of Duchenne muscular dystrophy ... remarkably current in the new techniques, a credit to the author. There is something for everyone interested in neuromuscular disease in this book. The book is extremely well written, and easy to read and I would recommend the book to anyone in the field ... a tour de force, a delight to possess.' Nigel G. Laing, Human Genetics Society of Australasia, March '94

'With the same fluency and flow which he achieved in the first edition, Alan Emery has succeeded in a masterly fashion in assimilating and digesting the essentials from all this new information and integrating it into this new volume. His vast personal experience both as a geneticist and a clinician are clearly apparent from the confidence as well as the sensitivity with which he has covered many of the topics ... a source of reference as well as an interesting and informative read.' Victor Dubowitz, Royal Postgraduate Medical School, London, Neuromuscular Disorders

'Professor Emery's book is a useful reference text for all of those involved in the care of patients with Duchenne muscular dystrophy or research into the muscular dystrophies. This text provides a rounded view of all of the many issues involved ... a useful starting point for those who care for Duchenne muscular dystrophy patients and their families who want to improve their knowledge about all aspects of the condition from a very clear and readable text.' Katherine Bushby, Journal of Medical Genetics

About the Author

Alan E. H. Emery, Research Director, European Neuromuscular Centre, Baarn.

Product Details

• Hardcover: 408 pages
• Publisher: Oxford University Press, USA; 2 edition (January 1, 1993)
• Language: English
• ISBN-10: 0192623702
• ISBN-13: 978-0192623706
• Product Dimensions: 9.6 x 6.4 x 1.1 inches
• Shipping Weight: 2 pounds
• Average Customer Review: 5.0 out of 5 stars  See all reviews (1 customer review)
• Amazon Best Sellers Rank: #5,482,495 in Books (See Top 100 in Books)

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Customer Reviews

Most Helpful Customer Reviews

0 of 2 people found the following review helpful:

5.0 out of 5 stars Excellent!!, February 8, 1999

By A Customer

This review is from: Duchenne Muscular Dystrophy (Monographs on Medical Genetics) (Paperback)

I thought that this book was a great source. I had a report on the subject, and it helped alot