THIS VACCINE CANNOT BE SHIPPED TO MINNESOTA. For the vaccination of healthy dogs against canine distemper, canine hepatitis, parainfluenza, parvovirus and adenovirus type 2. This is a modified live vaccine. Administer 1 ml of rehydrated vaccine subcutaneously or intramuscularly. Can be safely used on puppies of any age. Should start at or about 6 weeks of age. Due to the parainfluenza fraction a two dose regimen is recommended. Administer a second dose 2 to 3 weeks after initial dose. An annual revaccination with a single dose is recommended.